Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8986422 | 1.00 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1TSHRLMNAALB | |
| SCHEMBL6906196 | 0.95 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1TSHRLMNAALB | |
| Nonane SCHEMBL28716314 | 0.91 | MCHR1 (0.56) | ALDH1A1L3MBTL1TSHRLMNAALB | |
| Dodecane SCHEMBL7126605 | 0.91 | MCHR1 (0.56) | ALDH1A1L3MBTL1TSHRLMNAALB | |
| Tetradecane SCHEMBL29089041 | 0.91 | MCHR1 (0.56) | ALDH1A1L3MBTL1TSHRLMNAALB | |
| Decane SCHEMBL17004268 | 0.91 | MCHR1 (0.56) | ALDH1A1L3MBTL1TSHRLMNAALB | |
| Octane SCHEMBL356741 | 0.91 | MCHR1 (0.56) | ALDH1A1L3MBTL1TSHRLMNAALB | |
| Octane SCHEMBL8462698 | 0.91 | MCHR1 (0.56) | ALDH1A1L3MBTL1TSHRLMNAALB | |
| Heptane SCHEMBL8501523 | 0.91 | MCHR1 (0.56) | ALDH1A1L3MBTL1TSHRLMNAALB | |
| Undecane SCHEMBL28638565 | 0.91 | MCHR1 (0.56) | ALDH1A1L3MBTL1TSHRLMNAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736574-B1 | Thermoplastic resin composition comprising carbonate and acrylic resin | GEN ELECTRIC (US) | 2004-06-02 | — | — | EP | disclosed |
| US-6103827-A | A TRANSPARENT THERMOPLASTIC RESIN BLENDS | GENERAL ELECTRIC COMPANY (US) | 2000-08-15 | — | — | US | disclosed |
| US-5883194-A | RADIATION TRANSPARENT THERMOPLASTIC RESINS OF CARBONATE AND ESTER BLENDS WITH ACRYLATE RESINS AND CATALYSTS | GENERAL ELECTRIC COMPANY (US) | 1999-03-16 | — | — | US | disclosed |
| EP-0736574-A2 | Thermoplastic resin composition comprising carbonate and acrylic resin | GENERAL ELECTRIC COMPANY (US) | 1996-10-09 | — | — | EP | disclosed |