Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6909564 | 0.91 | PDE8B (1.00) | PDE8BPDE8A | |
| SCHEMBL6911029 | 0.90 | PDE8B (0.81) | PDE8BPDE8A | |
| SCHEMBL6911364 | 0.87 | PDE8B (0.71) | PDE8BPDE8A | |
| SCHEMBL6911266 | 0.86 | PDE8B (0.72) | PDE8BPDE8A | |
| SCHEMBL6910428 | 0.84 | PDE8B (1.00) | PDE8BPDE8A | |
| SCHEMBL6910056 | 0.81 | PDE8B (0.81) | PDE8B | |
| SCHEMBL6910604 | 0.81 | PDE8B (1.00) | PDE8BPDE8A | |
| SCHEMBL6909462 | 0.78 | PDE8B (1.00) | PDE8BPDE8A | |
| SCHEMBL6910951 | 0.78 | PDE8B (1.00) | PDE8BPDE8A | |
| SCHEMBL6910946 | 0.78 | PDE8B (1.00) | PDE8BPDE8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011058478-A1 | SUBSTITUTED TRIAZOLOPYRIMIDINES AS PDE8 INHIBITORS | PFIZER INC. (US) | 2011-05-19 | — | — | WO | disclosed |