Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | RORC | P51449 | 6/20 | 0.48 |
| ▸ | BCHE | P06276 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9271444 | 0.87 | HDAC3 (0.45) | RORCTSHRHDAC3HDAC1HDAC2 | |
| SCHEMBL330083 | 0.85 | HRH3 (0.68) | HRH3RORCBCHETSHRHSD17B10 | |
| SCHEMBL14385144 | 0.83 | MAPT (0.60) | HRH3RORCBCHE | |
| Hydrochloric Acid SCHEMBL17710415 | 0.83 | HRH3 (0.65) | HRH3RORCBCHETSHRHSD17B10 | |
| Water SCHEMBL28117059 | 0.83 | HRH3 (0.65) | HRH3RORCBCHETSHRHSD17B10 | |
| SCHEMBL24765013 | 0.82 | RORC (0.48) | HRH3RORCBCHETSHRHSD17B10 | |
| SCHEMBL8240347 | 0.81 | HRH3 (0.61) | HRH3RORCBCHETSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL3183297 | 0.79 | HRH3 (0.59) | HRH3RORCBCHETSHRHSD17B10 | |
| SCHEMBL9485158 | 0.78 | MAPT (0.61) | HRH3RORCBCHETSHRHSD17B10 | |
| SCHEMBL11197923 | 0.78 | HRH3 (0.59) | HRH3RORCBCHETSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011046771-A1 | SUBSTITUTED PIPERIDINES THAT INCREASE p53 ACTIVITY AND THE USES THEREOF | SCHERING CORPORATION (US) | 2011-04-21 | — | — | WO | disclosed |