Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 6/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.44 |
| ▸ | ADH1B | P00325 | 1/20 | 0.44 |
| ▸ | ADH1C | P00326 | 1/20 | 0.44 |
| ▸ | ADH1A | P07327 | 1/20 | 0.44 |
| ▸ | ADH7 | P40394 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 4/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18657229 | 0.89 | APP (0.50) | ADH1BADH1CADH1AADH7BCHE | |
| SCHEMBL6911524 | 0.82 | HRH3 (0.52) | RORCHRH3ACKR3BCHEHDAC3 | |
| SCHEMBL330083 | 0.81 | HRH3 (0.68) | RORCHRH3BCHETSHRHSD17B10 | |
| SCHEMBL11402252 | 0.80 | HRH3 (0.53) | RORCHRH3ACKR3BCHETSHR | |
| Water SCHEMBL28117059 | 0.79 | HRH3 (0.65) | RORCHRH3BCHETSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL17710415 | 0.79 | HRH3 (0.65) | RORCHRH3BCHETSHRHSD17B10 | |
| SCHEMBL15866364 | 0.78 | RORC (0.56) | RORCHRH3ACKR3BCHETSHR | |
| SCHEMBL9726709 | 0.77 | ADH1B (0.56) | ADH1BADH1CADH1AADH7TSHR | |
| SCHEMBL8240347 | 0.77 | HRH3 (0.61) | RORCHRH3BCHETSHRHSD17B10 | |
| SCHEMBL17346147 | 0.76 | HRH3 (0.45) | RORCHRH3ACKR3BCHETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4104901-A1 | 3-SUBSTITUTED 1H-PYRROLO[2,3-B]PYRIDINE AS GRK5 MODULATORS | Lead Discovery Center GmbH (DE) | 2022-12-21 | — | — | EP | disclosed |