Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPD | P32754 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398752 | 0.83 | HTR1A (0.50) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL4962154 | 0.81 | LMNA (0.39) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL5839420 | 0.81 | CCNB2 (0.51) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL6441776 | 0.81 | MAPT (0.54) | MAOBPOLBLMNASMN1; SMN2NPC1 | |
| SCHEMBL11852626 | 0.80 | NPC1 (0.48) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL28877513 | 0.80 | CCNB2 (0.53) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL10605128 | 0.79 | LMNA (0.43) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL4958314 | 0.78 | LMNA (0.39) | POLBLMNAHTR1AADRA1DADRA1A | |
| SCHEMBL27571443 | 0.78 | POLB (0.44) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL20607402 | 0.78 | POLB (0.43) | CCNB2CDK1CDK4CCNB1CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039409-A2 | COMPOSITION COMPRISING ACTIVATORS OF IK POTASSIUM CHANNELS AND CALCINEURIN ANTAGONISTS AND USE THEREOF | SWITCH BIOTECH AG (DE) | 2004-05-13 | — | — | WO | claimed |