SCHEMBL6911977

SCHEMBL6911977

FC(F)(F)N(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.41
TSHR P16473 1/20 0.41
NPSR1 Q6W5P4 1/20 0.36
ALOX15 P16050 1/20 0.36
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
MAPT P10636 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
CYP3A4 P08684 2/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
HTT P42858 2/20 0.35
KDM4E B2RXH2 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KIF11 P52732 1/20 0.35
CES1 P23141 1/20 0.33
HPGD P15428 2/20 0.32
PTPN1 P18031 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23044998 0.82 ALDH1A1 (0.44) ALDH1A1TSHRMEN1KMT2AMAPT
SCHEMBL9095150 0.81 CA4 (0.48) NPSR1KMT2AMAPTL3MBTL1KDM4E
SCHEMBL12574813 0.78 ALDH1A1 (0.38) ALDH1A1TSHRNPSR1ALOX15MEN1
SCHEMBL22169164 0.78 CYP3A4 (0.35) ALDH1A1TSHRALOX15MAPTL3MBTL1
SCHEMBL728216 0.77 ALDH1A1 (0.41) ALDH1A1TSHRNPSR1ALOX15MEN1
SCHEMBL30947663 0.77 ALDH1A1 (0.41) ALDH1A1TSHRNPSR1ALOX15MEN1
SCHEMBL5673228 0.76 TACR1 (0.39) ALDH1A1MEN1KMT2AKIF11HPGD
SCHEMBL10585744 0.75 MEN1 (0.35) ALDH1A1MEN1KMT2ATDP1
SCHEMBL1391905 0.75 ALDH1A1 (0.58) ALDH1A1TSHRMEN1KMT2AMAPT
SCHEMBL1391769 0.75 ALDH1A1 (0.32) ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106187890-B A method of acridone derivatives are catalyzed and synthesized altogether using palladium-copper 武汉大学 2018-09-21 CN claimed
CN-106187890-A A kind of method utilizing palladium copper to catalyze and synthesize acridone derivatives altogether 武汉大学 2016-12-07 CN claimed
WO-2023282236-A1 RARE EARTH COMPLEX 東ソー株式会社 2023-01-12 WO disclosed
CN-110177794-B Tetracarboxylic dianhydride, polyimide precursor resin and solution thereof, and polyimide and solution thereof JXTG能源株式会社 2021-12-28 CN disclosed
CN-106187890-B A method of acridone derivatives are catalyzed and synthesized altogether using palladium-copper 武汉大学 2018-09-21 CN disclosed
CN-108373416-A A kind of method of light/nickel concerted catalysis synthesis diaryl-amine 陕西师范大学 2018-08-07 CN disclosed
CN-106187890-A A kind of method utilizing palladium copper to catalyze and synthesize acridone derivatives altogether 武汉大学 2016-12-07 CN disclosed
CN-103171214-A Substrate structure with release layer and manufacturing method thereof CHI MEI CORP 2013-06-26 CN disclosed
EP-2473049-A1 BRUTON'S TYROSINE KINASE INHIBITORS Biogen Idec MA Inc. (US) 2012-07-11 EP disclosed
US-6822057-B2 OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG EXXON MOBIL CHEMICAL PATENTS INC. 2004-11-23 US disclosed
EP-1353907-A2 PHOSPHODIESTERASE 4 INHIBITORS Memory Pharmaceutical Corporation (US) 2003-10-22 EP disclosed
US-20020115806-A1 Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-22 US disclosed
US-20020111265-A1 GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-15 US disclosed
EP-0475676-B1 Electrophotographic member HITACHI CHEMICAL CO LTD (JP) 1996-04-03 EP disclosed
EP-0658157-A1 DIARYL PIPERAZINOACETAMIDE COMPOUNDS AS ANTIMUSCARINIC AGENTS MERRELL PHARMACEUTICALS INC. (US) 1995-06-21 EP disclosed
US-5403958-A Fluoroalkoxy-substituted diarylamines as intermediates for charge transfer compounds HITACHI CHEMICAL CO., LTD. (JP) 1995-04-04 US disclosed
US-5352834-A Fluorine-containing N,N,N*,N*-tetraarylbenzidine derivative as charge transport material for electrography HITACHI CHEMICAL COMPANY, LTD. (JP) 1994-10-04 US disclosed
WO-1994005648-A1 DIARYL PIPERAZINOACETAMIDE COMPOUNDS AS ANTIMUSCARINIC AGENTS MERRELL DOW PHARMACEUTICALS INC. (US) 1994-03-17 WO disclosed
US-5160487-A Tetraarylbenzidine derivative as charge transport compound HITACHI CHEMICAL COMPANY, LTD. (JP) 1992-11-03 US disclosed
EP-0475676-A1 Electrophotographic member HITACHI CHEMICAL CO., LTD. (JP) 1992-03-18 EP disclosed