Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6865235 | 0.81 | MEN1 (0.35) | ALDH1A1MEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL7871378 | 0.80 | ALDH1A1 (0.32) | ALDH1A1TSHRMAPTCYP3A4 | |
| SCHEMBL15014251 | 0.78 | ALDH1A1 (0.38) | ALDH1A1TSHRMEN1KMT2AHTT | |
| SCHEMBL6911977 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TSHRMEN1KMT2AHTT | |
| SCHEMBL30947663 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TSHRMEN1KMT2AHTT | |
| SCHEMBL3109136 | 0.74 | ALDH1A1 (0.39) | ALDH1A1TSHRMEN1KMT2AHTT | |
| SCHEMBL7875178 | 0.73 | ALDH1A1 (0.36) | ALDH1A1TSHRKIF11 | |
| SCHEMBL3615102 | 0.72 | ALDH1A1 (0.46) | ALDH1A1TSHRMEN1KMT2AALOX15 | |
| SCHEMBL816348 | 0.72 | ALDH1A1 (0.48) | ALDH1A1TSHRMAPTCYP2C19TDP1 | |
| SCHEMBL14392747 | 0.72 | APP (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2579870-B1 | TRKB AGONISTS AND METHODS OF USE | UNIV EMORY (US) | 2018-02-14 | — | — | EP | claimed |
| EP-2579870-A2 | TRKB AGONISTS AND METHODS OF USE | Emory University (US) | 2013-04-17 | — | — | EP | claimed |
| US-20130040947-A1 | TRKB AGONISTS AND METHODS OF USE | EMORY UNIVERSITY (US) | 2013-02-14 | — | — | US | claimed |
| WO-2011156479-A9 | TRKB AGONISTS AND METHODS OF USE | EMORY UNIVERSITY (US) | 2012-05-31 | — | — | WO | claimed |
| WO-2011156479-A2 | TRKB AGONISTS AND METHODS OF USE | EMORY UNIVERSITY (US) | 2011-12-15 | — | — | WO | claimed |
| JP-2011524383-A | — | — | 2011-09-01 | — | — | JP | claimed |
| US-20110118289-A1 | 6-1H-IMIDAZO-QUINAZOLINE AND QUINOLINES DERIVATIVES, NEW MAO INHIBITORS AND IMIDAZOLINE RECEPTOR LIGANDS | ROTTAPHARM S.P.A. (IT) | 2011-05-19 | — | — | US | claimed |
| EP-2315588-A1 | 6-1H-IMIDAZO-QUINAZOLINE AND QUINOLINES DERIVATIVES, NEW MAO INHIBITORS AND IMIDAZOLINE RECEPTOR LIGANDS | Rottapharm S.p.A. (IT) | 2011-05-04 | — | — | EP | claimed |
| WO-2009152868-A1 | 6-1H-IMIDAZO-QUINAZOLINE AND QUINOLINES DERIVATIVES, NEW MAO INHIBITORS AND IMIDAZOLINE RECEPTOR LIGANDS | ROTTAPHARM S.P.A. (IT) | 2009-12-23 | — | — | WO | claimed |
| US-5075378-A | Coating of an epoxy resin, fluorocarbon polymer fluorinated curing agent | THE STANDARD OIL COMPANY (US) | 1991-12-24 | — | — | US | claimed |
| US-5035970-A | Encapsulated toner compositions and processes thereof | XEROX CORPORATION (US) | 1991-07-30 | — | — | US | claimed |
| EP-2681789-B1 | FUEL CELL COMPRISING AT LEAST TWO STACKED PRINTED CIRCUIT BOARDS WITH A PLURALITY OF INTERCONNECTED FUEL CELL UNITS | IP2IPO INNOVATIONS LTD (GB) | 2025-06-25 | — | — | EP | disclosed |
| CN-120005240-A | Multilayer film, polyimide film and cover film package | 杜邦电子公司 | 2025-05-16 | — | — | CN | disclosed |
| CN-119767654-A | Cladding layer with polymer film and metal layer | 杜邦电子公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-119764455-A | Current collector and energy storage device | 杜邦电子公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-1999058497-A1 | SUBSTITUTED GUANIDINES AND DIAMINONITROETHENES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1999-11-18 | — | — | WO | disclosed |
| EP-0206951-B1 | PROCESS FOR THE PERFLUOROALKYLATION OF AROMATIC DERIVATIVES | RHONE-POULENC CHIMIE (FR) | 1990-03-21 | — | — | EP | disclosed |
| EP-0289797-A2 | Contact lens material | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-11-09 | — | — | EP | disclosed |
| EP-0206951-A2 | Process for the perfluoroalkylation of aromatic derivatives | RHONE-POULENC CHIMIE (FR) | 1986-12-30 | — | — | EP | disclosed |
| EP-0058009-A1 | Novel benzanilide derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1982-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118289-A1 | 6-1H-IMIDAZO-QUINAZOLINE AND QUINOLINES DERIVATIVES, NEW MAO INHIBITORS AND IMIDAZOLINE RECEPTOR LIGANDS | OPRM1, OPRD1, HTR3C | ALDH1A1 285/4885TSHR 395/4885MEN1 4669/4885 |
| US-20130040947-A1 | TRKB AGONISTS AND METHODS OF USE | NTRK2, BDNF, NTRK1 | ALDH1A1 1116/4885TSHR 318/4885MEN1 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.