Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15043690 | 0.95 | TSHR (0.64) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL14840165 | 0.87 | TSHR (0.50) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL28917038 | 0.83 | TSHR (0.46) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL21829113 | 0.82 | TSHR (0.57) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL10585663 | 0.81 | TSHR (0.65) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL19411061 | 0.80 | TSHR (0.50) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL29477898 | 0.80 | TSHR (0.59) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL4810333 | 0.80 | TSHR (0.53) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL13367691 | 0.79 | TSHR (0.57) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL10071424 | 0.78 | TSHR (0.74) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9175139-B2 | Alkoxy group-containing silicones with reactive functional groups of defined reactivity | WACKER CHEMICAL CORPORATION (US) | 2015-11-03 | — | — | US | disclosed |
| EP-1134251-B1 | Primer composition and method of bonding a sealing material onto a substrate | KANEKA CORP (JP) | 2004-10-20 | — | — | EP | disclosed |