Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TERT | O14746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179005 | 0.87 | TOP1 (0.54) | TOP1SMN1; SMN2RAB9AKDM4EALDH1A1 | |
| SCHEMBL179010 | 0.82 | EPHX2 (0.57) | TOP1SMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL6906984 | 0.82 | SMN1; SMN2 (0.49) | TOP1SMN1; SMN2RAB9AKDM4EALDH1A1 | |
| SCHEMBL179011 | 0.82 | TOP1 (0.58) | TOP1SMN1; SMN2RAB9AKDM4EALDH1A1 | |
| SCHEMBL179026 | 0.82 | TOP1 (0.58) | TOP1SMN1; SMN2RAB9AKDM4EALDH1A1 | |
| SCHEMBL5469490 | 0.81 | SMN1; SMN2 (0.66) | SMN1; SMN2RAB9AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL179090 | 0.80 | CCR5 (0.60) | TOP1SMN1; SMN2RAB9AGAATSHR | |
| SCHEMBL8232970 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL6905913 | 0.79 | GAA (0.63) | SMN1; SMN2RAB9AALDH1A1GAATSHR | |
| SCHEMBL179012 | 0.78 | IMPDH2 (0.54) | TOP1SMN1; SMN2RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1455734-A1 | COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES | Yu, Ruey J., Dr. (US) | 2004-09-15 | — | — | EP | claimed |
| WO-2003045338-A1 | COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES | YU RUEY J (US) | 2003-06-05 | — | — | WO | claimed |