Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146137 | 0.86 | KMT2A (0.42) | KMT2AMEN1SMN1; SMN2MAPTALOX15 | |
| SCHEMBL30434536 | 0.86 | KMT2A (0.42) | KMT2AMEN1SMN1; SMN2MAPTALOX15 | |
| SCHEMBL149433 | 0.75 | CD274 (0.43) | KMT2AMEN1SMN1; SMN2MAPTALOX15 | |
| SCHEMBL30434923 | 0.72 | CD274 (0.43) | KMT2AMEN1SMN1; SMN2MAPTALOX15 | |
| SCHEMBL144292 | 0.72 | CD274 (0.43) | KMT2AMEN1SMN1; SMN2MAPTALOX15 | |
| SCHEMBL690689 | 0.72 | ABCB1 (0.39) | KMT2AMEN1SMN1; SMN2MAPTHTT | |
| SCHEMBL148489 | 0.71 | ALDH1A1 (0.45) | SMN1; SMN2MAPTHTTALDH1A1KDM4E | |
| SCHEMBL21382342 | 0.68 | ALDH1A1 (0.48) | KMT2AMEN1SMN1; SMN2MAPTHTT | |
| SCHEMBL27868672 | 0.68 | ALDH1A1 (0.42) | KMT2ASMN1; SMN2HTTALDH1A1KDM4E | |
| SCHEMBL21957070 | 0.67 | HTT (0.67) | KMT2AMEN1SMN1; SMN2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421533-A1 | NOVEL ANTI-INFLAMMATORY AGENTS | RESVERLOGIX CORP. (CA) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010123975-A1 | NOVEL ANTI-INFLAMMATORY AGENTS | RESVERLOGIX CORP. (CA) | 2010-10-28 | — | — | WO | disclosed |