Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30434717 | 0.83 | AAK1 (0.40) | ABCB1MEN1KMT2APOLBPTPN1 | |
| SCHEMBL145071 | 0.83 | AAK1 (0.40) | ABCB1MEN1KMT2APOLBPTPN1 | |
| SCHEMBL27780036 | 0.77 | LCK (0.56) | MEN1KMT2AHPGDMAPTPOLB | |
| SCHEMBL2113203 | 0.75 | KDM4E (0.53) | KMT2AHPGDMAPTPOLBNPSR1 | |
| SCHEMBL691268 | 0.72 | KMT2A (0.46) | MEN1KMT2AHPGDMAPTALDH1A1 | |
| SCHEMBL14438192 | 0.71 | ACHE (0.43) | MEN1KMT2AHPGDMAPTPOLB | |
| SCHEMBL16229258 | 0.71 | CYP2C9 (0.49) | ABCB1MAPTCYP3A4NPSR1PTPN1 | |
| SCHEMBL505418 | 0.70 | LCK (0.56) | HPGDMAPTNPSR1TDP1PTPN1 | |
| SCHEMBL31079121 | 0.70 | LPAR1 (0.57) | MEN1KMT2AHPGDMAPTPOLB | |
| SCHEMBL14721362 | 0.70 | ALDH1A1 (0.52) | MEN1KMT2AMAPTPOLBGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421533-A1 | NOVEL ANTI-INFLAMMATORY AGENTS | RESVERLOGIX CORP. (CA) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010123975-A1 | NOVEL ANTI-INFLAMMATORY AGENTS | RESVERLOGIX CORP. (CA) | 2010-10-28 | — | — | WO | disclosed |