Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1985653 | 0.80 | AR (0.55) | CA2ADORA3ARHSD11B1AKR1C3 | |
| SCHEMBL15016568 | 0.80 | CA2 (0.41) | CA2HTR1ASIGMAR1ADRA2AADRA2B | |
| SCHEMBL29773128 | 0.78 | CYP2C9 (0.49) | CA2ADORA3ARHSD11B1AKR1C3 | |
| SCHEMBL531764 | 0.78 | CYP2C9 (0.49) | CA2ADORA3ARHSD11B1AKR1C3 | |
| SCHEMBL27319090 | 0.76 | CYP19A1 (0.49) | KDM4ECYP19A1HSD17B10 | |
| SCHEMBL9074495 | 0.76 | CA2 (0.39) | CA2ADORA3ARHSD11B1AKR1C3 | |
| Flavane SCHEMBL29478071 | 0.75 | ESR1 (0.51) | ADORA3ARHTR1ASIGMAR1ADRA2A | |
| Flavane SCHEMBL14394530 | 0.75 | ESR1 (0.51) | ADORA3ARHTR1ASIGMAR1ADRA2A | |
| Flavane SCHEMBL27595228 | 0.75 | ESR1 (0.51) | ADORA3ARHTR1ASIGMAR1ADRA2A | |
| Flavane SCHEMBL123287 | 0.75 | ESR1 (0.51) | ADORA3ARHTR1ASIGMAR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070743-A2 | Optical polycarbonate compositions | GE PLASTICS JAPAN LIMITED (JP) | 2001-01-24 | — | — | EP | claimed |
| US-5276109-A | Molding materials with transparency | GENERAL ELECTRIC COMPANY (US) | 1994-01-04 | — | — | US | claimed |
| EP-0520806-A2 | Optical polycarbonate compositions | GE PLASTICS JAPAN LIMITED (JP) | 1992-12-30 | — | — | EP | claimed |
| EP-0736574-B1 | Thermoplastic resin composition comprising carbonate and acrylic resin | GEN ELECTRIC (US) | 2004-06-02 | — | — | EP | disclosed |
| EP-0685526-B1 | Fire-resistant polycarbonate resin composition | GEN ELECTRIC (US) | 2001-08-29 | — | — | EP | disclosed |
| US-6197917-B1 | Method for manufacturing polycarbonate for optical use | GENERAL ELECTRIC COMPANY | 2001-03-06 | — | — | US | disclosed |
| EP-1070743-A2 | Optical polycarbonate compositions | GE PLASTICS JAPAN LIMITED (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-6103827-A | A TRANSPARENT THERMOPLASTIC RESIN BLENDS | GENERAL ELECTRIC COMPANY (US) | 2000-08-15 | — | — | US | disclosed |
| US-6043310-A | FIRE-RESISTANT POLYCARBONATE RESIN COMPOSITION CONTAINING LIQUID CRYSTAL POLYMER, FLAME RETARDANT, POLYTETRAFLUOROETHYLENE. | GENERAL ELECTRIC COMPANY (US) | 2000-03-28 | — | — | US | disclosed |
| EP-0561630-B1 | Polycarbonate resin compositions for optical use | GE PLASTICS JAPAN LTD (JP) | 1999-12-29 | — | — | EP | disclosed |
| US-5883194-A | RADIATION TRANSPARENT THERMOPLASTIC RESINS OF CARBONATE AND ESTER BLENDS WITH ACRYLATE RESINS AND CATALYSTS | GENERAL ELECTRIC COMPANY (US) | 1999-03-16 | — | — | US | disclosed |
| US-5403878-A | With alpha olefin oligomer and acidic sulfur compound; mold releasing, thermostability | CITIBANK, N.A., AS COLLATERAL AGENT | 1995-04-04 | — | — | US | disclosed |
| US-5389713-A | Polycarbonate formed by melt polymerization of aromatic dihydroxy compound and carbonate diester, alpha-olefin oligomer, acidic sulfur-containing compound | GE PLASTICS JAPAN (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0605157-A2 | Resin compositions | GE PLASTICS JAPAN LIMITED (JP) | 1994-07-06 | — | — | EP | disclosed |
| EP-0605194-A2 | Transparent polycarbonate-polyester-blends | GE PLASTICS JAPAN LIMITED (JP) | 1994-07-06 | — | — | EP | disclosed |
| US-5276109-A | Molding materials with transparency | GENERAL ELECTRIC COMPANY (US) | 1994-01-04 | — | — | US | disclosed |
| EP-0561638-A1 | Optical-grade polycarbonate resin compositions | GE PLASTICS JAPAN LIMITED (JP) | 1993-09-22 | — | — | EP | disclosed |
| EP-0561629-A2 | Polycarbonate resin compositions | GE PLASTICS JAPAN LIMITED (JP) | 1993-09-22 | — | — | EP | disclosed |
| EP-0561630-A2 | Polycarbonate resin compositions for optical use | GE PLASTICS JAPAN LIMITED (JP) | 1993-09-22 | — | — | EP | disclosed |
| EP-0520806-A2 | Optical polycarbonate compositions | GE PLASTICS JAPAN LIMITED (JP) | 1992-12-30 | — | — | EP | disclosed |