Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 4/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6911622 | 0.87 | FTO (0.43) | FTOAKR1C1OPRM1OPRD1BACE1 | |
| SCHEMBL7753016 | 0.87 | FTO (0.39) | FTOAKR1C1HSP90AA1DHFRTYMS | |
| SCHEMBL6911177 | 0.84 | AKR1C1 (0.41) | FTOAKR1C1OPRM1OPRD1BACE1 | |
| SCHEMBL6914734 | 0.77 | FTO (0.41) | FTOAKR1C1OPRM1OPRD1BACE1 | |
| SCHEMBL5736550 | 0.73 | BACE1 (0.41) | OPRM1OPRD1BACE1CTSD | |
| SCHEMBL4518818 | 0.73 | BACE1 (0.51) | BACE1CTSDAKR1B1 | |
| SCHEMBL6913273 | 0.69 | CYP3A4 (0.41) | FTOAKR1C1HSP90AA1 | |
| SCHEMBL6906553 | 0.68 | BACE1 (0.43) | AKR1C1BACE1HSP90AA1CTSDDHFR | |
| SCHEMBL4520263 | 0.68 | BACE1 (0.40) | BACE1CTSDAKR1B1 | |
| SCHEMBL11348885 | 0.68 | FTO (0.55) | FTOOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736574-B1 | Thermoplastic resin composition comprising carbonate and acrylic resin | GEN ELECTRIC (US) | 2004-06-02 | — | — | EP | disclosed |
| EP-0685526-B1 | Fire-resistant polycarbonate resin composition | GEN ELECTRIC (US) | 2001-08-29 | — | — | EP | disclosed |
| US-6197917-B1 | Method for manufacturing polycarbonate for optical use | GENERAL ELECTRIC COMPANY | 2001-03-06 | — | — | US | disclosed |
| EP-1070743-A2 | Optical polycarbonate compositions | GE PLASTICS JAPAN LIMITED (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-6103827-A | A TRANSPARENT THERMOPLASTIC RESIN BLENDS | GENERAL ELECTRIC COMPANY (US) | 2000-08-15 | — | — | US | disclosed |
| US-6043310-A | FIRE-RESISTANT POLYCARBONATE RESIN COMPOSITION CONTAINING LIQUID CRYSTAL POLYMER, FLAME RETARDANT, POLYTETRAFLUOROETHYLENE. | GENERAL ELECTRIC COMPANY (US) | 2000-03-28 | — | — | US | disclosed |
| EP-0561630-B1 | Polycarbonate resin compositions for optical use | GE PLASTICS JAPAN LTD (JP) | 1999-12-29 | — | — | EP | disclosed |
| US-5883194-A | RADIATION TRANSPARENT THERMOPLASTIC RESINS OF CARBONATE AND ESTER BLENDS WITH ACRYLATE RESINS AND CATALYSTS | GENERAL ELECTRIC COMPANY (US) | 1999-03-16 | — | — | US | disclosed |
| EP-0736574-A2 | Thermoplastic resin composition comprising carbonate and acrylic resin | GENERAL ELECTRIC COMPANY (US) | 1996-10-09 | — | — | EP | disclosed |
| EP-0736558-A2 | A polyester polycarbonate composition which is transparent and has outstanding thermal stability | GENERAL ELECTRIC COMPANY (US) | 1996-10-09 | — | — | EP | disclosed |
| US-5418269-A | Made by ester interchange, mold release, thermal stability, little discoloration on molding, disks | GE PLASTICS JAPAN (JP) | 1995-05-23 | — | — | US | disclosed |
| US-5403878-A | With alpha olefin oligomer and acidic sulfur compound; mold releasing, thermostability | CITIBANK, N.A., AS COLLATERAL AGENT | 1995-04-04 | — | — | US | disclosed |
| US-5389713-A | Polycarbonate formed by melt polymerization of aromatic dihydroxy compound and carbonate diester, alpha-olefin oligomer, acidic sulfur-containing compound | GE PLASTICS JAPAN (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0605157-A2 | Resin compositions | GE PLASTICS JAPAN LIMITED (JP) | 1994-07-06 | — | — | EP | disclosed |
| EP-0605194-A2 | Transparent polycarbonate-polyester-blends | GE PLASTICS JAPAN LIMITED (JP) | 1994-07-06 | — | — | EP | disclosed |
| US-5276109-A | Molding materials with transparency | GENERAL ELECTRIC COMPANY (US) | 1994-01-04 | — | — | US | disclosed |
| EP-0561638-A1 | Optical-grade polycarbonate resin compositions | GE PLASTICS JAPAN LIMITED (JP) | 1993-09-22 | — | — | EP | disclosed |
| EP-0561629-A2 | Polycarbonate resin compositions | GE PLASTICS JAPAN LIMITED (JP) | 1993-09-22 | — | — | EP | disclosed |
| EP-0561630-A2 | Polycarbonate resin compositions for optical use | GE PLASTICS JAPAN LIMITED (JP) | 1993-09-22 | — | — | EP | disclosed |
| EP-0520806-A2 | Optical polycarbonate compositions | GE PLASTICS JAPAN LIMITED (JP) | 1992-12-30 | — | — | EP | disclosed |