SCHEMBL6912914

SCHEMBL6912914

c1ccc2c(c1)Sc1ccccc1C21OO1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 4/20 0.42
GAA P10253 3/20 0.42
MAPT P10636 3/20 0.42
BCHE P06276 3/20 0.42
MAOA P21397 2/20 0.42
ACHE P22303 2/20 0.42
MEN1 O00255 1/20 0.42
CYP1A2 P05177 1/20 0.42
POLB P06746 1/20 0.42
CYP3A4 P08684 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
CNR1 P21554 1/20 0.42
PTGS1 P23219 1/20 0.42
SLC6A2 P23975 1/20 0.42
HTR2C P28335 1/20 0.42
PTGS2 P35354 1/20 0.42
SNCA P37840 1/20 0.42
SLC6A3 Q01959 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21709994 0.79 ALDH1A1 (0.40) NOX1GAAMAPTBCHEMAOA
SCHEMBL15522245 0.79 CYBB (0.53) NOX1MAPTMEN1CYP1A2CYP3A4
SCHEMBL30291021 0.76 GAA (0.47) NOX1GAAMAPTBCHEMAOA
SCHEMBL20539744 0.76 NOX1 (0.48) NOX1GAAMAPTBCHEMAOA
SCHEMBL21635988 0.73 POLB (0.36) NOX1GAAMAPTBCHEMAOA
SCHEMBL12215367 0.72 MEN1 (0.32) NOX1GAAMAPTBCHEMAOA
SCHEMBL23085145 0.72 NOX1 (0.44) NOX1GAAMAPTBCHEMAOA
SCHEMBL10306784 0.72 NOX1 (0.44) NOX1GAAMAPTBCHEMAOA
SCHEMBL8984697 0.72 NOX1 (0.44) NOX1GAAMAPTBCHEMAOA
SCHEMBL798117 0.72 NOX1 (0.44) NOX1GAAMAPTBCHEMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014071836-A1 9H-THIOXANTHEN-9-ONE OXIDE DERIVATIVE, PREPARATION METHOD AND USE THEREOF 中国科学院理化技术研究所 (CN) 2014-05-15 WO disclosed
US-6727294-B2 RADIATION TRANSPARENT MOLDING MATERIALS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2004-04-27 US disclosed
EP-0794218-B1 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENG PLASTICS CORP (JP) 2003-10-15 EP disclosed
EP-0753540-B1 Polycarbonate resin composition MITSUBISHI ENG PLASTICS CORP (JP) 2003-06-11 EP disclosed
US-6359028-B1 USED IN MEDICAL EQUIPMENT, DISCOLORATION INHIBITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2002-03-19 US disclosed
US-20010034419-A1 Radiation transparent molding materials MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2001-10-25 US disclosed
US-6040367-A EXCELLENT RESISTANCE TO AN IONIZING RADIATION, IN WHICH HETEROCYCLIC COMPOUND CONTAINING OXYMETHYLENE UNITS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2000-03-21 US disclosed
US-5977206-A Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-11-02 US disclosed
US-5948838-A 0.01 TO 5 PARTS BY WEIGHT OF A COMPOUND CONTAINING OXYMETHYLENE UNIT MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-09-07 US disclosed
EP-0794218-A2 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-09-10 EP disclosed
EP-0753540-A2 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-01-15 EP disclosed