SCHEMBL8984697

SCHEMBL8984697

ClC1(Cl)c2ccccc2Sc2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 5/20 0.44
MAPT P10636 4/20 0.44
BCHE P06276 3/20 0.44
GAA P10253 3/20 0.44
ACHE P22303 2/20 0.44
MAOA P21397 2/20 0.44
MEN1 O00255 1/20 0.44
CYP1A2 P05177 1/20 0.44
POLB P06746 1/20 0.44
CYP3A4 P08684 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
CNR1 P21554 1/20 0.44
PTGS1 P23219 1/20 0.44
SLC6A2 P23975 1/20 0.44
HTR2C P28335 1/20 0.44
PTGS2 P35354 1/20 0.44
SNCA P37840 1/20 0.44
SLC6A3 Q01959 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20539744 0.78 NOX1 (0.48) NOX1MAPTBCHEGAAACHE
SCHEMBL8369793 0.76 S100A4 (0.46) CYP1A2ALOX12TDP1S100A4ALDH1A1
SCHEMBL28506971 0.75 NOX1 (0.41) NOX1MAPTBCHEGAAACHE
SCHEMBL10306784 0.74 NOX1 (0.44) NOX1MAPTBCHEGAAACHE
SCHEMBL30928004 0.74 NOX1 (0.44) NOX1MAPTBCHEGAAACHE
SCHEMBL23085145 0.74 NOX1 (0.44) NOX1MAPTBCHEGAAACHE
SCHEMBL798117 0.74 NOX1 (0.44) NOX1MAPTBCHEGAAACHE
Ammonia Solution, Strong SCHEMBL9520970 0.74 S100A4 (0.44) TDP1S100A4ALDH1A1CACNB4CACNA1A
SCHEMBL21880253 0.73 BCHE (0.35) NOX1MAPTBCHEGAAACHE
SCHEMBL6912914 0.72 NOX1 (0.42) NOX1MAPTBCHEGAAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218102-A1 COMPOSITIONS WITH HIGH REFRACTIVE INDEX AND ABBE NUMBER Johnson & Johnson Surgical Vision, Inc. 2024-07-04 US disclosed
US-20240209129-A1 OPHTHALMIC LENS MATERIALS AND DEVICES MADE THEREOF Johnson & Johnson Surgical Vision, Inc. 2024-06-27 US disclosed
US-20240209129-A1 OPHTHALMIC LENS MATERIALS AND DEVICES MADE THEREOF Johnson & Johnson Surgical Vision, Inc. 2024-06-27 US disclosed
WO-2024116106-A1 OPHTHALMIC LENS MATERIALS AND DEVICES MADE THEREOF Johnson & Johnson Surgical Vision, Inc. (US) 2024-06-06 WO disclosed
US-20240067825-A1 POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT JOHNSON & JOHNSON VISION CARE (US) 2024-02-29 US disclosed
WO-2023242688-A1 OPHTHALMIC DEVICES CONTAINING PHOTOSTABLE MIMICS OF MACULAR PIGMENT AND OTHER VISIBLE LIGHT FILTERS JOHNSON & JOHNSON VISION CARE, INC. (US) 2023-12-21 WO disclosed
US-11820899-B2 Polymerizable absorbers of UV and high energy visible light JOHNSON & JOHNSON VISION CARE, INC. (US) 2023-11-21 US disclosed
US-11795252-B2 Compositions with high refractive index and Abbe number Johnson & Johnson Surgical Vision, Inc. (US) 2023-10-24 US disclosed
US-11795252-B2 Compositions with high refractive index and Abbe number Johnson & Johnson Surgical Vision, Inc. (US) 2023-10-24 US disclosed
US-20230288728-A1 MULTIFOCAL CONTACT LENS DISPLAYING IMPROVED VISION ATTRIBUTES MAHADEVAN SHIVKUMAR (US) 2023-09-14 US disclosed
WO-2022090857-A1 COMPOSITIONS WITH HIGH REFRACTIVE INDEX AND ABBE NUMBER Johnson & Johnson Surgical Vision, Inc. (US) 2022-05-05 WO disclosed
WO-2021038369-A1 MULTIFOCAL CONTACT LENS DISPLAYING IMPROVED VISION ATTRIBUTES JOHNSON & JOHNSON VISION CARE, INC. (US) 2021-03-04 WO disclosed
WO-2021038368-A1 CONTACT LENS DISPLAYING IMPROVED VISION ATTRIBUTES JOHNSON & JOHNSON VISION CARE, INC. (US) 2021-03-04 WO disclosed
US-20210061934-A1 CONTACT LENS DISPLAYING IMPROVED VISION ATTRIBUTES JOHNSON & JOHNSON VISION CARE, INC. 2021-03-04 US disclosed
WO-2020261021-A1 POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT JOHNSON & JOHNSON VISION CARE, INC. (US) 2020-12-30 WO disclosed
WO-2020225686-A1 HIGH REACTIVE INDEX, HIGH ABBE COMPOSITIONS Johnson & Johnson Surgical Vision, Inc. (US) 2020-11-12 WO disclosed
US-5578737-A SUBSTITUTED FLUORENES, MONOMERS FOR HIGH PERFORMANCE POLYMERS THE DOW CHEMICAL COMPANY (US) 1996-11-26 US disclosed
US-5387725-A Chlorinating compounds having acidic protons with a perchloro-alkane and aqueous base in the presence of a tetraalkyl-ammonium hydroxide phase transfer catalyst THE DOW CHEMICAL COMPANY (US) 1995-02-07 US disclosed
EP-0611366-A1 CHLORINATION PROCESS, ALKYLATION OF PRODUCTS OF SAID PROCESS AND SOME PRODUCTS THEREOF THE DOW CHEMICAL COMPANY (US) 1994-08-24 EP disclosed
WO-1993009074-A2 CHLORINATION PROCESS, ALKYLATION OF PRODUCTS OF SAID PROCESS AND SOME PRODUCTS THEREOF THE DOW CHEMICAL COMPANY (US) 1993-05-13 WO disclosed