Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6053728 | 1.00 | NPC1 (0.32) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL27482198 | 0.86 | — | — | |
| SCHEMBL6913287 | 0.81 | ALOX5 (0.32) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL6810423 | 0.79 | NPC1 (0.31) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL8163903 | 0.79 | NOS2 (0.31) | NPC1HPGDMAPK1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL28029831 | 0.79 | NPC1 (0.31) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL27832567 | 0.79 | NPC1 (0.31) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL27446594 | 0.79 | NPC1 (0.31) | NPC1HPGDMAPK1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL6811751 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL967492 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1189435-C | Novel transition metal compound and catalyst containing the same for polymerization of olefins | JAPAN POLYOLEFINS CO LTD (JP) | 2005-02-16 | — | — | CN | disclosed |
| EP-0969010-B1 | Transition metal compound and catalyst containing the same for polymerization of olefins | JAPAN POLYOLEFINS CO LTD (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-6352953-B1 | TRANSITION METAL COMPLEX HAVING 5-MEMBERED RING FORMED BY TRANSITION METAL COMPOUND OF GROUP IVB, TWO CARBONS, METAL OF GROUP IIIA AND HYDROGEN | JAPAN POLYOLEFINS CO., LTD. (JP) | 2002-03-05 | — | — | US | disclosed |
| US-6150544-A | Transition metal compound and catalyst containing the same for polymerization of olefins | JAPAN POLYOLEFINS CO., LTD. (JP) | 2000-11-21 | — | — | US | disclosed |
| CN-1240782-A | Novel transition metal compound and catalyst containing the same for polymerization of olefins | JAPAN POLYOLEFINS CO LTD (JP) | 2000-01-12 | — | — | CN | disclosed |
| EP-0969010-A2 | Transition metal compound and catalyst containing the same for polymerization of olefins | Japan Polyolefins Co., Ltd. (JP) | 2000-01-05 | — | — | EP | disclosed |