Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6909900 | 0.85 | TSHR (0.53) | TSHRLMNAKDM4EHPGDALDH1A1 | |
| SCHEMBL6438478 | 0.81 | LMNA (0.60) | TSHRLMNAKDM4EHPGDALDH1A1 | |
| SCHEMBL4189992 | 0.80 | LMNA (0.58) | TSHRLMNAKDM4EHPGDALDH1A1 | |
| SCHEMBL27908807 | 0.80 | TSHR (0.63) | TSHRLMNAKDM4EHPGDALDH1A1 | |
| SCHEMBL28013496 | 0.80 | LMNA (0.58) | TSHRLMNAKDM4EHPGDALDH1A1 | |
| SCHEMBL9579136 | 0.75 | LMNA (0.68) | TSHRLMNAKDM4EHPGDALDH1A1 | |
| Methyl Salicylate SCHEMBL28202612 | 0.75 | TSHR (0.88) | TSHRLMNAKDM4EHPGDALDH1A1 | |
| SCHEMBL10501149 | 0.75 | LMNA (0.67) | TSHRLMNAKDM4EHPGDALDH1A1 | |
| SCHEMBL28260858 | 0.73 | ALDH1A1 (0.68) | TSHRLMNAKDM4EHPGDALDH1A1 | |
| SCHEMBL5815155 | 0.73 | TSHR (0.54) | TSHRLMNAKDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839041-B1 | CYCLO-OXYGENASE INHIBITOR AND AMIDINE DERIVATIVE SALTS, PREPARATION METHOD THEREFOR, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID SALTS | CONSEILS DE RECH SET D APPLIC (FR) | 2004-04-14 | — | — | EP | claimed |
| US-6063807-A | Cyclo-oxygenase inhibitor and amidine derivatives salts, preparation method therefor, use thereof as drugs, and pharmaceutical compositions containing said salts | SOCIETE DE CONSEILS DE RECHERCHES D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2000-05-16 | — | — | US | claimed |
| CN-1187056-C | Cyclo-oxygenase inhibitor and amidine derivative salts, preparation method thereof, use thereof as drugs, and pharmaceutical compositions containing said salts | SOD CONSEILS RECH APPLIC (FR) | 2005-02-02 | — | — | CN | disclosed |
| US-6063807-A | Cyclo-oxygenase inhibitor and amidine derivatives salts, preparation method therefor, use thereof as drugs, and pharmaceutical compositions containing said salts | SOCIETE DE CONSEILS DE RECHERCHES D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2000-05-16 | — | — | US | disclosed |
| CN-1190890-A | Cyclo-oxygenase inhibitor and amidine derivative salts, preparation method thereof, use thereof as drugs, and pharmaceutical compositions containing said salts | SOD CONSEILS RECH APPLIC (FR) | 1998-08-19 | — | — | CN | disclosed |