SCHEMBL691317

SCHEMBL691317

Cc1cc(N)n(C(C)C)n1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.44
CYP1A2 P05177 2/20 0.42
CYP2C19 P33261 2/20 0.42
MAPK1 P28482 1/20 0.42
ALDH1A1 P00352 4/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
LMNA P02545 2/20 0.38
SMN1; SMN2 Q16637 4/20 0.37
PKM P14618 1/20 0.37
RAB9A P51151 3/20 0.37
MAPT P10636 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
PDE1A P54750 1/20 0.36
PDE1B Q01064 1/20 0.36
PDE1C Q14123 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11747616 0.83 POLB (0.41) POLBCYP1A2CYP2C19MAPK1ALDH1A1
SCHEMBL11333878 0.83 POLB (0.41) POLBCYP1A2CYP2C19MAPK1ALDH1A1
SCHEMBL11831648 0.79 POLB (0.39) POLBCYP1A2CYP2C19MAPK1ALDH1A1
SCHEMBL11685425 0.79 POLB (0.39) POLBCYP1A2CYP2C19MAPK1ALDH1A1
SCHEMBL11687312 0.79 POLB (0.43) POLBCYP1A2CYP2C19MAPK1ALDH1A1
SCHEMBL11687591 0.78 ALDH1A1 (0.42) POLBCYP1A2CYP2C19MAPK1ALDH1A1
SCHEMBL11687368 0.78 POLB (0.38) POLBCYP1A2CYP2C19MAPK1ALDH1A1
SCHEMBL1695266 0.78 POLB (0.38) POLBCYP1A2CYP2C19MAPK1ALDH1A1
SCHEMBL11686958 0.78 POLB (0.38) POLBCYP1A2CYP2C19MAPK1ALDH1A1
SCHEMBL691341 0.78 POLB (0.38) POLBCYP1A2CYP2C19MAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119053889-A Multilayer film, method for producing same, polarizing plate, and organic electroluminescent image display device 日本瑞翁株式会社 2024-11-29 CN disclosed
US-12018021-B2 Thiophene derivatives for the treatment of disorders caused by IgE UCB Biopharma SRL (BE) 2024-06-25 US disclosed
WO-2024024467-A1 LIQUID COMPOSITION AND OPTICAL FILM 日本ゼオン株式会社 2024-02-01 WO disclosed
WO-2023233958-A1 MULTILAYER FILM AND METHOD FOR MANUFACTURING SAME, POLARIZING PLATE, AND ORGANIC ELECTROLUMINESCENT IMAGE DISPLAY DEVICE 日本ゼオン株式会社 2023-12-07 WO disclosed
CN-117043163-A Pyrrolopyrimidine or pyrrolopyridine derivative and medical application thereof 希格生科(深圳)有限公司 2023-11-10 CN disclosed
CN-111443415-B Polarizing plate 住友化学株式会社 2023-08-01 CN disclosed
WO-2023141511-A1 POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 VANDERBILT UNIVERSITY (US) 2023-07-27 WO disclosed
CN-116332905-A (S) -N-phenyl-1- (pyridin-2-yl) pyrrolidine-2-carboxamide derivatives 上海翊石医药科技有限公司 2023-06-27 CN disclosed
CN-115304607-B Pyrazolopyrimidine derivative and process for preparing same 华南农业大学 2023-06-27 CN disclosed
WO-2023054256-A1 MULTILAYER FILM, OPTICAL MULTILAYER FILM, AND MANUFACTURING METHOD 日本ゼオン株式会社 2023-04-06 WO disclosed
US-4243584-A Monoazo dyestuffs containing diazo component substituted by disulfimide and trifluoromethyl groups BAYER AKTIENGESELLSCHAFT (DE) 1981-01-06 US disclosed
US-4234594-A Pyrazolyl amino imidazolines as antihypertensive agents ABBOTT LABORATORIES (US) 1980-11-18 US disclosed
US-4226773-A Pyrazolyl amino imidazolines as diuretic agents ABBOTT LABORATORIES (US) 1980-10-07 US disclosed
US-4171367-A ANTIINFLAMMATORY ABBOTT LABORATORIES (US) 1979-10-16 US disclosed
US-4159265-A Phenylazopyrazolo dyestuffs including disulfimide substituent BAYER AKTIENGESELLSCHAFT (DE) 1979-06-26 US disclosed
US-4113718-A Basic azo dyes CIBA-GEIGY CORPORATION (US) 1978-09-12 US disclosed
US-4055557-A MONOAZO DYES BAYER AKTIENGESELLSCHAFT (DT) 1977-10-25 US disclosed
US-4026931-A AZO DYES, FIBER-REACTIVE; INDOLE OR 5-AMINO-PYRAZOLE COUPLING COMPONENT BAYER AKTIENGESELLSCHAFT (DT) 1977-05-31 US disclosed
US-4017479-A Cationic indazole-azo-5-amino pyrazole dyestuffs CIBA-GEIGY AG (CH) 1977-04-12 US disclosed
US-4006127-A Cationic diazacyanine dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12018021-B2 Thiophene derivatives for the treatment of disorders caused by IgE TSLP, CYSLTR1, CYSLTR2 POLB 3826/4885CYP1A2 329/4885CYP2C19 202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.