Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11747616 | 0.83 | POLB (0.41) | POLBCYP1A2CYP2C19MAPK1ALDH1A1 | |
| SCHEMBL11333878 | 0.83 | POLB (0.41) | POLBCYP1A2CYP2C19MAPK1ALDH1A1 | |
| SCHEMBL11831648 | 0.79 | POLB (0.39) | POLBCYP1A2CYP2C19MAPK1ALDH1A1 | |
| SCHEMBL11685425 | 0.79 | POLB (0.39) | POLBCYP1A2CYP2C19MAPK1ALDH1A1 | |
| SCHEMBL11687312 | 0.79 | POLB (0.43) | POLBCYP1A2CYP2C19MAPK1ALDH1A1 | |
| SCHEMBL11687591 | 0.78 | ALDH1A1 (0.42) | POLBCYP1A2CYP2C19MAPK1ALDH1A1 | |
| SCHEMBL11687368 | 0.78 | POLB (0.38) | POLBCYP1A2CYP2C19MAPK1ALDH1A1 | |
| SCHEMBL1695266 | 0.78 | POLB (0.38) | POLBCYP1A2CYP2C19MAPK1ALDH1A1 | |
| SCHEMBL11686958 | 0.78 | POLB (0.38) | POLBCYP1A2CYP2C19MAPK1ALDH1A1 | |
| SCHEMBL691341 | 0.78 | POLB (0.38) | POLBCYP1A2CYP2C19MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119053889-A | Multilayer film, method for producing same, polarizing plate, and organic electroluminescent image display device | 日本瑞翁株式会社 | 2024-11-29 | — | — | CN | disclosed |
| US-12018021-B2 | Thiophene derivatives for the treatment of disorders caused by IgE | UCB Biopharma SRL (BE) | 2024-06-25 | — | — | US | disclosed |
| WO-2024024467-A1 | LIQUID COMPOSITION AND OPTICAL FILM | 日本ゼオン株式会社 | 2024-02-01 | — | — | WO | disclosed |
| WO-2023233958-A1 | MULTILAYER FILM AND METHOD FOR MANUFACTURING SAME, POLARIZING PLATE, AND ORGANIC ELECTROLUMINESCENT IMAGE DISPLAY DEVICE | 日本ゼオン株式会社 | 2023-12-07 | — | — | WO | disclosed |
| CN-117043163-A | Pyrrolopyrimidine or pyrrolopyridine derivative and medical application thereof | 希格生科(深圳)有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-111443415-B | Polarizing plate | 住友化学株式会社 | 2023-08-01 | — | — | CN | disclosed |
| WO-2023141511-A1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | VANDERBILT UNIVERSITY (US) | 2023-07-27 | — | — | WO | disclosed |
| CN-116332905-A | (S) -N-phenyl-1- (pyridin-2-yl) pyrrolidine-2-carboxamide derivatives | 上海翊石医药科技有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-115304607-B | Pyrazolopyrimidine derivative and process for preparing same | 华南农业大学 | 2023-06-27 | — | — | CN | disclosed |
| WO-2023054256-A1 | MULTILAYER FILM, OPTICAL MULTILAYER FILM, AND MANUFACTURING METHOD | 日本ゼオン株式会社 | 2023-04-06 | — | — | WO | disclosed |
| US-4243584-A | Monoazo dyestuffs containing diazo component substituted by disulfimide and trifluoromethyl groups | BAYER AKTIENGESELLSCHAFT (DE) | 1981-01-06 | — | — | US | disclosed |
| US-4234594-A | Pyrazolyl amino imidazolines as antihypertensive agents | ABBOTT LABORATORIES (US) | 1980-11-18 | — | — | US | disclosed |
| US-4226773-A | Pyrazolyl amino imidazolines as diuretic agents | ABBOTT LABORATORIES (US) | 1980-10-07 | — | — | US | disclosed |
| US-4171367-A | ANTIINFLAMMATORY | ABBOTT LABORATORIES (US) | 1979-10-16 | — | — | US | disclosed |
| US-4159265-A | Phenylazopyrazolo dyestuffs including disulfimide substituent | BAYER AKTIENGESELLSCHAFT (DE) | 1979-06-26 | — | — | US | disclosed |
| US-4113718-A | Basic azo dyes | CIBA-GEIGY CORPORATION (US) | 1978-09-12 | — | — | US | disclosed |
| US-4055557-A | MONOAZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-10-25 | — | — | US | disclosed |
| US-4026931-A | AZO DYES, FIBER-REACTIVE; INDOLE OR 5-AMINO-PYRAZOLE COUPLING COMPONENT | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | disclosed |
| US-4017479-A | Cationic indazole-azo-5-amino pyrazole dyestuffs | CIBA-GEIGY AG (CH) | 1977-04-12 | — | — | US | disclosed |
| US-4006127-A | Cationic diazacyanine dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12018021-B2 | Thiophene derivatives for the treatment of disorders caused by IgE | TSLP, CYSLTR1, CYSLTR2 | POLB 3826/4885CYP1A2 329/4885CYP2C19 202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.