Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2225582 | 0.87 | HDAC6 (0.52) | HDAC6HDAC1MEN1KMT2AHDAC4 | |
| SCHEMBL3090259 | 0.79 | HDAC6 (0.65) | HDAC6HDAC1MEN1KMT2AHPGD | |
| SCHEMBL13838101 | 0.78 | TIPARP (0.46) | SLC6A7 | |
| SCHEMBL2225623 | 0.75 | HDAC6 (0.46) | HDAC6HDAC1HDAC4 | |
| SCHEMBL13115595 | 0.74 | KDM4E (0.67) | MEN1CYP2C9KMT2ACYP1A2CYP2C19 | |
| SCHEMBL3575181 | 0.72 | SLC6A7 (0.69) | MEN1CYP2C9KMT2ACYP1A2CYP2C19 | |
| SCHEMBL23244365 | 0.71 | ME2 (0.66) | MEN1KMT2ALMNAALDH1A1MGLL | |
| SCHEMBL1108658 | 0.70 | KDM4E (0.62) | MEN1CYP2C9KMT2ACYP1A2CYP2C19 | |
| SCHEMBL1108662 | 0.70 | CYP1A2 (0.64) | MEN1CYP2C9KMT2ACYP1A2CYP2C19 | |
| SCHEMBL2201554 | 0.70 | HDAC6 (0.57) | HDAC6HDAC1MEN1CYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011088192-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2011-07-21 | — | — | WO | disclosed |