Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2065834 | 0.94 | TDP1 (0.65) | SMN1; SMN2TSHRTDP1POLBCYP2D6 | |
| SCHEMBL9073539 | 0.90 | STS (0.53) | SMN1; SMN2TSHRTDP1POLBCYP2D6 | |
| SCHEMBL9705238 | 0.86 | TSHR (0.67) | SMN1; SMN2TSHRTDP1POLBCYP2D6 | |
| SCHEMBL19146 | 0.85 | TDP1 (0.73) | SMN1; SMN2TDP1CA1CA2CA9 | |
| SCHEMBL7981247 | 0.85 | TDP1 (0.73) | SMN1; SMN2TDP1CA1CA2CA9 | |
| SCHEMBL28560984 | 0.85 | POLB (0.72) | SMN1; SMN2TSHRTDP1POLBCYP2D6 | |
| SCHEMBL4393906 | 0.84 | TDP1 (0.56) | SMN1; SMN2TDP1CA1CA2CA9 | |
| SCHEMBL28934632 | 0.83 | TDP1 (0.70) | SMN1; SMN2TDP1CA1CA2CA9 | |
| SCHEMBL1674227 | 0.83 | TDP1 (0.70) | SMN1; SMN2TDP1CA1CA2CA9 | |
| Ammonia Solution, Strong SCHEMBL28247173 | 0.83 | TDP1 (0.70) | SMN1; SMN2TDP1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727294-B2 | RADIATION TRANSPARENT MOLDING MATERIALS | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2004-04-27 | — | — | US | disclosed |
| US-20010034419-A1 | Radiation transparent molding materials | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2001-10-25 | — | — | US | disclosed |
| US-5274009-A | Also containing a polyalkylene oxide | BAYER AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | disclosed |
| US-5246495-A | Material for improving the strength of cementitious material | LOC SYSTEMS, LTD. (LP) (US) | 1993-09-21 | — | — | US | disclosed |