SCHEMBL4393906

SCHEMBL4393906

O=S(=O)(Oc1ccccc1)c1ccc(O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.56
LTA4H P09960 1/20 0.48
NR1H2 P55055 1/20 0.48
BAX Q07812 1/20 0.48
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
ESR1 P03372 1/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA9 Q16790 2/20 0.47
MAPT P10636 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.45
LMNA P02545 2/20 0.45
HTT P42858 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
GAA P10253 1/20 0.44
PKM P14618 1/20 0.44
ALDH1A1 P00352 1/20 0.44
MAOB P27338 1/20 0.44
NPC1 O15118 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9495042 0.92 TDP1 (0.67) TDP1LTA4HNR1H2BAXMEN1
SCHEMBL28793114 0.90 TDP1 (0.65) TDP1LTA4HNR1H2BAXMEN1
SCHEMBL872834 0.90 MEN1 (0.56) TDP1MEN1KMT2AESR1CA1
SCHEMBL3181209 0.89 TDP1 (0.59) TDP1MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL19146 0.85 TDP1 (0.73) TDP1KMT2ACA1CA2CA9
SCHEMBL7981247 0.85 TDP1 (0.73) TDP1KMT2ACA1CA2CA9
SCHEMBL6913684 0.84 SMN1; SMN2 (0.58) TDP1MEN1KMT2ACA1CA2
SCHEMBL11598565 0.84 MEN1 (0.56) TDP1MEN1KMT2AESR1MAPT
SCHEMBL1674227 0.83 TDP1 (0.70) TDP1KMT2ACA1CA2CA9
SCHEMBL28934632 0.83 TDP1 (0.70) TDP1KMT2ACA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112177377-A Environment-friendly house leakage maintenance method 安徽墨砂工程修缮技术有限公司 2021-01-05 CN claimed
CN-112177377-A Environment-friendly house leakage maintenance method 安徽墨砂工程修缮技术有限公司 2021-01-05 CN disclosed
CN-111979863-A Construction method for filling high embankment by using foam lightweight concrete adjacent to high-speed rail 中铁八局集团第三工程有限公司 2020-11-24 CN disclosed
US-20190033319-A1 BINDING DOMAIN MAPPING George Mason Research Foundation, Inc. (US) 2019-01-31 US disclosed
CN-106565953-A Preparation method of PA6 system polyamide thermoplastic elastomer 东华大学 2017-04-19 CN disclosed
US-20150338417-A1 BINDING DOMAIN MAPPING GEORGE MASON UNIVERSITY 2015-11-26 US disclosed
US-20150338417-A1 BINDING DOMAIN MAPPING GEORGE MASON UNIVERSITY 2015-11-26 US disclosed
US-7632781-B2 Color developer for heat sensitive recording, process for producing the color development and heat sensitive recording material NICCA CHEMICAL CO., LTD. (JP) 2009-12-15 US disclosed
EP-1738919-B1 THERMOSENSITIVE RECORDING DEVELOPER, AND PROCESS FOR PRODUCING THE SAME NICCA CHEMICAL CO (JP) 2008-05-28 EP disclosed
CN-100360325-C Multicolor thermal recording medium JUJO PAPER CO LTD (JP) 2008-01-09 CN disclosed
US-20070219094-A1 Color Developer for Heat Sensitive Recording, Process for Producing the Color Developer and Heat Sensitive Recording Material NICCA CHEMICAL CO., L TD. (JP) 2007-09-20 US disclosed
EP-1738919-A1 THERMOSENSITIVE RECORDING DEVELOPER, PROCESS FOR PRODUCING THE SAME AND THERMOSENSITIVE RECORDING MATERIAL Nicca Chemical Co., Ltd. (JP) 2007-01-03 EP disclosed
CN-1638973-A multicolor thermosensitive recording medium JUJO PAPER CO LTD (JP) 2005-07-13 CN disclosed
JP-2004114366-A DEVELOPER AND THERMOSENSITIVE RECORDING MATERIAL CONTAINING THE DEVELOPER KONISHI KAGAKU IND CO LTD 2004-04-15 JP disclosed
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed
US-4287189-A USEFUL AS PESTICIDES ROHM AND HAAS COMPANY (US) 1981-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190033319-A1 BINDING DOMAIN MAPPING SNRPE, HSPBP1, CNBP TDP1 301/4885LTA4H 4593/4885NR1H2 4039/4885
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 TDP1 3063/4885LTA4H 1285/4885NR1H2 3722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.