Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 9/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADK | P55263 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814034 | 0.84 | NOS1 (0.56) | NOS1MEN1KMT2ATSHRNPC1 | |
| SCHEMBL5514818 | 0.83 | NOS1 (0.78) | NOS1ADK | |
| SCHEMBL5516535 | 0.70 | NOS1 (1.00) | NOS1ADK | |
| SCHEMBL5512351 | 0.69 | NOS1 (0.75) | NOS1ALDH1A1NPC1RAB9A | |
| SCHEMBL4460914 | 0.68 | NOS1 (0.42) | NOS1ALDH1A1TSHRNPC1RAB9A | |
| Water SCHEMBL6484545 | 0.68 | NOS1 (0.73) | NOS1ALDH1A1NPC1RAB9A | |
| SCHEMBL5513451 | 0.68 | NOS1 (1.00) | NOS1ALDH1A1 | |
| SCHEMBL5510752 | 0.67 | NOS1 (0.72) | NOS1ALDH1A1NPC1RAB9A | |
| Water SCHEMBL6484322 | 0.66 | NOS1 (0.70) | NOS1ALDH1A1NPC1RAB9A | |
| SCHEMBL7823397 | 0.66 | NOS1 (0.54) | NOS1NPC1PDGFRBKDRFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144412-B1 | IMMUNOSUPPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | 4 AZA BIOSCIENCE NV (BE) | 2004-09-29 | — | — | EP | claimed |