Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021556 | 0.85 | F2 (0.43) | — | |
| SCHEMBL6886916 | 0.81 | TRHR (0.35) | TRHR | |
| SCHEMBL12771027 | 0.80 | HDAC4 (0.41) | TRHR | |
| SCHEMBL6913290 | 0.79 | — | — | |
| SCHEMBL8133669 | 0.76 | PREP (0.41) | EPHX1 | |
| SCHEMBL14432929 | 0.74 | EPHX1 (0.36) | TRHREPHX1 | |
| SCHEMBL8272952 | 0.74 | EPHX1 (0.36) | TRHREPHX1 | |
| SCHEMBL8161391 | 0.74 | ELANE (0.43) | — | |
| SCHEMBL8133784 | 0.73 | ELANE (0.40) | EPHX1 | |
| SCHEMBL8274139 | 0.73 | ELANE (0.40) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011002807-A1 | HCV PROTEASE INHIBITORS AND USES THEREOF | AVILA THERAPEUTICS, INC. (US) | 2011-01-06 | — | — | WO | disclosed |
| WO-2009082697-A1 | HCV PROTEASE INHIBITORS AND USES THEREOF | AVILA THERAPEUTICS, INC. (US) | 2009-07-02 | — | — | WO | disclosed |