Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6911038 | 0.83 | HMGCR (0.51) | HMGCRGPR55NR1I2TNFRSF1AMEN1 | |
| SCHEMBL6914359 | 0.82 | HMGCR (0.50) | HMGCRGPR55NR1I2MEN1KMT2A | |
| SCHEMBL9390284 | 0.80 | GPR55 (0.45) | HMGCRGPR55NR1I2TNFRSF1AMEN1 | |
| SCHEMBL9390295 | 0.80 | GPR55 (0.45) | HMGCRGPR55NR1I2TNFRSF1AMEN1 | |
| SCHEMBL6916160 | 0.80 | HMGCR (0.51) | HMGCRGPR55NR1I2MEN1KMT2A | |
| SCHEMBL9390290 | 0.79 | GPR55 (0.44) | HMGCRGPR55NR1I2TNFRSF1AMEN1 | |
| SCHEMBL6917719 | 0.78 | GABBR2 (0.52) | HMGCRGPR55NR1I2TNFRSF1AGABBR2 | |
| Butane SCHEMBL9220686 | 0.77 | GPR55 (0.42) | HMGCRGPR55NR1I2TNFRSF1AGAA | |
| SCHEMBL6911195 | 0.77 | HMGCR (0.47) | HMGCRGPR55NR1I2TNFRSF1AMEN1 | |
| SCHEMBL6916348 | 0.76 | HMGCR (0.46) | HMGCRGPR55NR1I2TNFRSF1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026245-A2 | SUBSTITUTED PHOSPHONATE COMPOUNDS HAVING BONE ANABOLIC ACTIVITY | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | claimed |
| EP-0638084-A1 | SUBSTITUTED PHOSPHONATES, THE PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1995-02-15 | — | — | EP | claimed |
| WO-1994019358-A1 | SUBSTITUTED PHOSPHONATES, THE PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1994-09-01 | — | — | WO | claimed |