Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100878 | 0.81 | ALDH1A1 (0.40) | LMNAALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL692305 | 0.80 | CA12 (0.32) | LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL691310 | 0.77 | POLB (0.39) | LMNATSHRALDH1A1KDM4EHPGD | |
| SCHEMBL691571 | 0.74 | LCK (0.42) | TSHRALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6529415 | 0.71 | LMNA (0.71) | LMNATSHRALDH1A1KDM4EHPGD | |
| SCHEMBL11139940 | 0.70 | ALDH1A1 (0.36) | LMNATSHRALDH1A1KDM4EHPGD | |
| SCHEMBL10868449 | 0.70 | ALDH1A1 (0.39) | LMNATSHRALDH1A1KDM4EHPGD | |
| SCHEMBL10389334 | 0.69 | ALDH1A1 (0.37) | LMNAALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL691281 | 0.66 | HSD17B10 (0.34) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL29389290 | 0.65 | APEX1 (0.48) | LMNATSHRALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421501-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND USE THEREOF | The Procter & Gamble Company (US) | 2012-02-29 | — | — | EP | claimed |
| WO-2010123863-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2010-10-28 | — | — | WO | claimed |
| EP-2421501-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND USE THEREOF | The Procter & Gamble Company (US) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010123863-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2010-10-28 | — | — | WO | disclosed |