SCHEMBL69146

SCHEMBL69146

O=C(O)/C=C/c1cccc(/C=C/C(=O)O)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.74
HDAC3 O15379 3/20 0.74
HDAC4 P56524 3/20 0.74
HDAC1 Q13547 3/20 0.74
HDAC7 Q8WUI4 3/20 0.74
HDAC2 Q92769 3/20 0.74
HDAC10 Q969S8 3/20 0.74
HDAC11 Q96DB2 3/20 0.74
HDAC8 Q9BY41 3/20 0.74
HDAC6 Q9UBN7 3/20 0.74
HDAC9 Q9UKV0 3/20 0.74
HDAC5 Q9UQL6 3/20 0.74
HCAR2 Q8TDS4 2/20 0.74
TNKS O95271 1/20 0.74
TNKS2 Q9H2K2 1/20 0.74
KDM4E B2RXH2 6/20 0.61
ALDH1A1 P00352 5/20 0.61
HSD17B10 Q99714 3/20 0.61
CYP2C9 P11712 3/20 0.61
CA12 O43570 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL271386 1.00 NPSR1 (0.74) NPSR1HDAC3HDAC4HDAC1HDAC7
SCHEMBL27771748 0.94 HDAC3 (0.79) NPSR1HDAC3HDAC4HDAC1HDAC7
SCHEMBL2323099 0.92 NPSR1 (0.65) NPSR1HDAC3HDAC4HDAC1HDAC7
SCHEMBL2323106 0.92 NPSR1 (0.65) NPSR1HDAC3HDAC4HDAC1HDAC7
SCHEMBL11212503 0.90 NPSR1 (0.62) NPSR1HDAC3HDAC4HDAC1HDAC7
SCHEMBL11212504 0.90 NPSR1 (0.62) NPSR1HDAC3HDAC4HDAC1HDAC7
SCHEMBL27543377 0.90 HDAC3 (0.67) NPSR1HDAC3HDAC4HDAC1HDAC7
SCHEMBL9633777 0.88 NPSR1 (0.61) NPSR1HDAC3HDAC4HDAC1HDAC7
SCHEMBL9633774 0.88 NPSR1 (0.61) NPSR1HDAC3HDAC4HDAC1HDAC7
SCHEMBL10504122 0.87 NPSR1 (0.65) NPSR1HDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0644232-B1 Free radical cured rubber GOODYEAR TIRE & RUBBER (US) 1997-03-05 EP claimed
US-11220475-B2 Monomers from biomass NDSU RESEARCH FOUNDATION (US) 2022-01-11 US disclosed
US-11220475-B2 Monomers from biomass NDSU RESEARCH FOUNDATION (US) 2022-01-11 US disclosed
US-20210198175-A9 NOVEL MONOMERS FROM BIOMASS NDSU RESEARCH FOUNDATION (US) 2021-07-01 US disclosed
US-20210198175-A9 NOVEL MONOMERS FROM BIOMASS NDSU RESEARCH FOUNDATION (US) 2021-07-01 US disclosed
US-20200140368-A1 NOVEL MONOMERS FROM BIOMASS NDSU RESEARCH FOUNDATION (US) 2020-05-07 US disclosed
US-20200140368-A1 NOVEL MONOMERS FROM BIOMASS NDSU RESEARCH FOUNDATION (US) 2020-05-07 US disclosed
US-20180093939-A9 NOVEL MONOMERS FROM BIOMASS NDSU RESEARCH FOUNDATION (US) 2018-04-05 US disclosed
US-20180093939-A9 NOVEL MONOMERS FROM BIOMASS NDSU RESEARCH FOUNDATION (US) 2018-04-05 US disclosed
US-20180093939-A9 NOVEL MONOMERS FROM BIOMASS NDSU RESEARCH FOUNDATION (US) 2018-04-05 US disclosed
WO-2016022943-A2 NOVEL MONOMERS FROM BIOMASS NDSU RESEARCH FOUNDATION (US) 2016-02-11 WO disclosed
WO-2013161984-A1 DIAMINE, POLYMER, LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学工業株式会社 (JP) 2013-10-31 WO disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
EP-0799827-B1 ACRYLAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME KYORIN SEIYAKU KK (JP) 2004-05-12 EP disclosed
US-5786486-A ANTIMICROBIAL, ANTITUMOR AGENTS KYORIN PHARMACEUTICAL CO., LTD. (JP) 1998-07-28 US disclosed
EP-0799827-A1 ACRYLAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME KYORIN PHARMACEUTICAL CO., LTD. (JP) 1997-10-08 EP disclosed
US-5670493-A ANGIOGENESIS INHIBITORS ADIR ET COMPAGNIE (FR) 1997-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210198175-A9 NOVEL MONOMERS FROM BIOMASS DCXR, MANBA, PGLS NPSR1 4572/4885HDAC3 2171/4885HDAC4 2409/4885
US-20180093939-A9 NOVEL MONOMERS FROM BIOMASS DCXR, MANBA, PGLS NPSR1 4572/4885HDAC3 2171/4885HDAC4 2409/4885
US-20200140368-A1 NOVEL MONOMERS FROM BIOMASS DCXR, MANBA, PGLS NPSR1 4572/4885HDAC3 2171/4885HDAC4 2409/4885
US-11220475-B2 Monomers from biomass DCXR, MGAM, ALG1 NPSR1 4620/4885HDAC3 1601/4885HDAC4 2114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.