Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6919537 | 0.74 | XDH (0.44) | XDHSLC22A12 | |
| SCHEMBL6914592 | 0.73 | XDH (0.37) | XDHSLC22A12HTTGSK3BNOTUM | |
| SCHEMBL2830780 | 0.68 | MAP2K1 (0.48) | MAP2K1XDHSLC22A12HTTNOTUM | |
| Hydrochloric Acid SCHEMBL7951893 | 0.67 | MAP2K1 (0.47) | MAP2K1XDHSLC22A12HTTNOTUM | |
| SCHEMBL3157619 | 0.66 | XDH (0.53) | MAP2K1XDHSLC22A12HTTNOTUM | |
| SCHEMBL40282 | 0.66 | CA12 (0.58) | KMT2AMTOR | |
| SCHEMBL29532021 | 0.66 | CA12 (0.58) | KMT2AMTOR | |
| SCHEMBL13283750 | 0.65 | MAP2K1 (0.51) | MAP2K1XDHSLC22A12HTTNOTUM | |
| SCHEMBL6353963 | 0.65 | KMT2A (0.62) | HTTKMT2AF2PLGPLAU | |
| SCHEMBL29441888 | 0.65 | GSK3B (0.62) | XDHSLC22A12HTTGSK3BMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |