SCHEMBL6353963

SCHEMBL6353963

N#Cc1ccc(NC(=O)c2ccccc2)c(C(=O)O)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.62
MEN1 O00255 5/20 0.62
MAPT P10636 4/20 0.62
TDP1 Q9NUW8 3/20 0.62
PKM P14618 2/20 0.62
GRIK1 P39086 1/20 0.62
LTC4S Q16873 1/20 0.61
ALB P02768 1/20 0.58
F2 P00734 1/20 0.58
PLG P00747 1/20 0.58
PLAU P00749 1/20 0.58
KLKB1 P03952 1/20 0.58
PRSS1 P07477 1/20 0.58
SERPINE1 P05121 4/20 0.57
GFER P55789 1/20 0.54
MCL1 Q07820 1/20 0.52
BCL2A1 Q16548 1/20 0.52
HTT P42858 2/20 0.51
AKR1C4 P17516 2/20 0.50
AKR1C3 P42330 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6359401 0.93 ALB (0.63) KMT2AMEN1MAPTTDP1PKM
SCHEMBL6348677 0.92 SERPINE1 (0.66) KMT2AMEN1MAPTTDP1PKM
SCHEMBL6349987 0.92 ALB (0.57) KMT2AMEN1MAPTTDP1PKM
SCHEMBL6346687 0.90 ALB (0.60) KMT2AMEN1MAPTTDP1PKM
SCHEMBL6359203 0.90 KMT2A (0.58) KMT2AMEN1MAPTTDP1PKM
SCHEMBL6351469 0.89 AKR1C2 (0.66) KMT2AMEN1MAPTTDP1PKM
SCHEMBL6350083 0.88 SERPINE1 (0.68) KMT2AMEN1MAPTALBF2
SCHEMBL6348543 0.87 ALB (0.58) KMT2AMEN1MAPTTDP1PKM
SCHEMBL6349507 0.87 MEN1 (0.57) KMT2AMEN1PKMSERPINE1GFER
SCHEMBL6353195 0.87 KMT2A (0.52) KMT2AMEN1MAPTTDP1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050113450-A1 Antibacterial agents PHARMACIA & UPJOHN COMPANY 2005-05-26 US claimed
WO-2004018414-A2 ANTIBACTERIAL AGENTS PHARMACIA & UPJOHN COMPANY LLC (US) 2004-03-04 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050113450-A1 Antibacterial agents CLPP, SPOUT1, SAMHD1 KMT2A 3645/4885MEN1 3274/4885MAPT 4753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.