SCHEMBL69153

SCHEMBL69153

Oc1ccc(-c2ccccc2)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 1.00
ESR2 Q92731 6/20 0.65
BACE1 P56817 1/20 0.64
BCL2L1 Q07817 2/20 0.61
ALDH1A1 P00352 1/20 0.61
HPGD P15428 1/20 0.61
HSD17B10 Q99714 1/20 0.61
HSP90AA1 P07900 1/20 0.59
GFER P55789 1/20 0.54
KMT2A Q03164 1/20 0.54
MMP3 P08254 1/20 0.52
ESR1 P03372 6/20 0.50
HSP90AB1 P08238 1/20 0.50
CHEK1 O14757 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29629264 1.00 ALOX5 (1.00) ALOX5ESR2BACE1BCL2L1ALDH1A1
Methane SCHEMBL26968809 0.98 ALOX5 (0.95) ALOX5ESR2BACE1BCL2L1ALDH1A1
SCHEMBL22280682 0.95 ALOX5 (0.91) ALOX5ESR2BACE1BCL2L1ALDH1A1
Ethane SCHEMBL27724868 0.95 ALOX5 (0.91) ALOX5ESR2BACE1BCL2L1ALDH1A1
Bromomethane SCHEMBL28284579 0.93 ALOX5 (0.87) ALOX5ESR2BACE1BCL2L1ALDH1A1
Formaldehyde SCHEMBL27517414 0.93 ALOX5 (0.87) ALOX5ESR2BACE1BCL2L1ALDH1A1
Chloromethane SCHEMBL28112788 0.93 ALOX5 (0.87) ALOX5ESR2BACE1BCL2L1ALDH1A1
SCHEMBL5002666 0.91 ALOX5 (0.83) ALOX5ESR2BACE1BCL2L1ALDH1A1
Sulfur Dioxide SCHEMBL28723541 0.91 ALOX5 (0.83) ALOX5ESR2BACE1BCL2L1ALDH1A1
Phenol SCHEMBL28301521 0.89 ALOX5 (0.80) ALOX5ESR2BACE1BCL2L1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 428 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116354980-A 2' -phenyl-5 (6) -carboxyfluorescein and preparation method thereof 苏州诺维康生物科技有限公司 2023-06-30 CN claimed
US-10040914-B2 Composites and epoxy resins based on aryl substituted compounds HEXION INC. (US) 2018-08-07 US claimed
US-20170051119-A1 COMPOSITES AND EPOXY RESINS BASED ON ARYL SUBSTITUTED COMPOUNDS Westlake Epoxy Inc. 2017-02-23 US claimed
US-9499692-B2 Composites and epoxy resins based on aryl substituted compounds HEXION INC. (US) 2016-11-22 US claimed
US-9382379-B2 Melt polymerization reactor system and method SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-07-05 US claimed
CN-105622915-A Melt polymerization reactor system and method SABIC INNOVATIVE PLASTICS IP 2016-06-01 CN claimed
US-20160039971-A1 MELT POLYMERIZATION REACTOR SYSTEM AND METHOD SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-02-11 US claimed
EP-2559719-B1 MELT POLYMERIZATION REACTOR SYSTEM AND METHOD SABIC GLOBAL TECHNOLOGIES BV (NL) 2015-09-16 EP claimed
CN-102516518-B Method of preparing polycarbonate SABIC INNOVATIVE PLASTICS IP 2014-12-31 CN claimed
WO-2014186279-A1 COMPOSITES AND EPOXY RESINS BASED ON ARYL SUBSTITUTED COMPOUNDS MOMENTIVE SPECIALTY CHEM INC (US) 2014-11-20 WO claimed
WO-2000042134-A1 NON-PHOSPHOROUS, NON-METALLIC ANTI-WEAR COMPOUND AND FRICTION MODIFIER INTERNATIONAL LUBRICANTS, INC. (US) 2000-07-20 WO claimed
WO-1999061563-A1 FUEL LUBRICITY ADDITIVES INTERNATIONAL LUBRICANTS, INC. (US) 1999-12-02 WO claimed
US-5151458-A Molding materials for liquid crystal resins BAYER AKTIENGESELLSCHAFT (DE) 1992-09-29 US claimed
US-5143956-A Blends with low molecular weight liquid crystals BAYER AKTIENGESELLSCHAFT (DE) 1992-09-01 US claimed
US-5102935-A With low molecular weight, liquid crystalline esters and/or ester amides BAYER AKTIENGESELLSCHAFT (DE) 1992-04-07 US claimed
EP-0464351-A2 Polycarbonate, polyestercarbonate and polyester moulding compositions with high melt flow BAYER AG (DE) 1992-01-08 EP claimed
EP-0444295-A1 Low-viscosity polyamide mouldings BAYER AG (DE) 1991-09-04 EP claimed
EP-0444292-A2 Easy fluoring polyamide moulding compositions BAYER AG (DE) 1991-09-04 EP claimed
EP-0398052-A2 Low-viscosity polyarylene sulfide mouldings BAYER AG (DE) 1990-11-22 EP claimed
EP-0359037-A2 Low-viscosity polyamide mouldings and mixtures BAYER AG (DE) 1990-03-21 EP claimed