Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 1.00 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.65 |
| ▸ | BACE1 | P56817 | 1/20 | 0.64 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 6/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69153 | 1.00 | ALOX5 (1.00) | ALOX5ESR2BACE1BCL2L1ALDH1A1 | |
| Methane SCHEMBL26968809 | 0.98 | ALOX5 (0.95) | ALOX5ESR2BACE1BCL2L1ALDH1A1 | |
| SCHEMBL22280682 | 0.95 | ALOX5 (0.91) | ALOX5ESR2BACE1BCL2L1ALDH1A1 | |
| Ethane SCHEMBL27724868 | 0.95 | ALOX5 (0.91) | ALOX5ESR2BACE1BCL2L1ALDH1A1 | |
| Bromomethane SCHEMBL28284579 | 0.93 | ALOX5 (0.87) | ALOX5ESR2BACE1BCL2L1ALDH1A1 | |
| Formaldehyde SCHEMBL27517414 | 0.93 | ALOX5 (0.87) | ALOX5ESR2BACE1BCL2L1ALDH1A1 | |
| Chloromethane SCHEMBL28112788 | 0.93 | ALOX5 (0.87) | ALOX5ESR2BACE1BCL2L1ALDH1A1 | |
| SCHEMBL5002666 | 0.91 | ALOX5 (0.83) | ALOX5ESR2BACE1BCL2L1ALDH1A1 | |
| Sulfur Dioxide SCHEMBL28723541 | 0.91 | ALOX5 (0.83) | ALOX5ESR2BACE1BCL2L1ALDH1A1 | |
| Phenol SCHEMBL28301521 | 0.89 | ALOX5 (0.80) | ALOX5ESR2BACE1BCL2L1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119385991-A | Application of [1,1' -biphenyl ] -2, 4-diol in medicines for inhibiting proliferation of melanoma cells | 大连大学 | 2025-02-07 | — | — | CN | claimed |
| EP-4251600-A2 | CANNABINOID DERIVATIVES AND THEIR USE FOR THE TREATMENT OF INFLAMMATION AND/OR PAIN AND/OR OBESITY | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) | 2023-10-04 | — | — | EP | claimed |
| WO-2022113071-A2 | CANNABINOID DERIVATIVES AND THEIR USE THE TREATMENT OF INFLAMMATION AND/OR PAIN AND/OR OBESITY | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2022-06-02 | — | — | WO | claimed |
| US-20250326771-A1 | PIPERAZINE DERIVATIVES USEFUL IN HIV THERAPY | VIIV HEALTHCARE CO (US) | 2025-10-23 | — | — | US | disclosed |
| CN-119385991-A | Application of [1,1' -biphenyl ] -2, 4-diol in medicines for inhibiting proliferation of melanoma cells | 大连大学 | 2025-02-07 | — | — | CN | disclosed |
| CN-119385991-A | Application of [1,1' -biphenyl ] -2, 4-diol in medicines for inhibiting proliferation of melanoma cells | 大连大学 | 2025-02-07 | — | — | CN | disclosed |
| CN-119385991-A | Application of [1,1' -biphenyl ] -2, 4-diol in medicines for inhibiting proliferation of melanoma cells | 大连大学 | 2025-02-07 | — | — | CN | disclosed |
| WO-2024246911-A1 | CANNABINOID DERIVATIVES AND USES THEREOF IN THE TREATMENT OF FUNGAL INFECTIONS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2024-12-05 | — | — | WO | disclosed |
| WO-2023033741-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2023-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250326771-A1 | PIPERAZINE DERIVATIVES USEFUL IN HIV THERAPY | CCR5, THPO, IL5 | ALOX5 1735/4885ESR2 4085/4885BACE1 3577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.