Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MTTP | P55157 | 10/20 | 0.54 |
| ▸ | APOB | P04114 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | UGCG | Q16739 | 1/20 | 0.48 |
| ▸ | MDH1 | P40925 | 1/20 | 0.47 |
| ▸ | MDH2 | P40926 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6259942 | 0.89 | POLB (0.55) | GAAPOLBMTTPAPOBSMN1; SMN2 | |
| SCHEMBL13351330 | 0.85 | KDM4E (0.59) | GAAPOLBMTTPAPOBSMN1; SMN2 | |
| SCHEMBL6274011 | 0.85 | GAA (0.53) | GAAPOLBMTTPAPOBSMN1; SMN2 | |
| SCHEMBL6796286 | 0.83 | MTTP (0.54) | GAAPOLBMTTPAPOBSMN1; SMN2 | |
| SCHEMBL6794905 | 0.81 | MTTP (0.52) | GAAPOLBMTTPAPOBSMN1; SMN2 | |
| SCHEMBL6789850 | 0.81 | PTPN1 (0.59) | GAAPOLBMTTPAPOBSMN1; SMN2 | |
| SCHEMBL6800981 | 0.81 | SMO (0.60) | GAAPOLBMTTPAPOB | |
| SCHEMBL6644462 | 0.81 | GAA (0.47) | GAAPOLBMTTPAPOBSMN1; SMN2 | |
| SCHEMBL31393757 | 0.80 | CHRNB2 (0.71) | GAAPOLBMTTPAPOBSMN1; SMN2 | |
| SCHEMBL6789828 | 0.79 | PTGS1 (0.58) | GAAMTTPAPOBSMN1; SMN2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040132745-A1 | Microsomal triglyceride transfer protein inhibitor | PFIZER INC | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132745-A1 | Microsomal triglyceride transfer protein inhibitor | MTTP, CETP, APOB | GAA 523/4885POLB 2297/4885MTTP 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.