Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.66 |
| ▸ | MAOB | P27338 | 12/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6915699 | 1.00 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL6915703 | 1.00 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL8208400 | 0.87 | ALDH1A1 (0.68) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL19827992 | 0.87 | ALDH1A1 (0.68) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL9448356 | 0.85 | ALDH1A1 (0.66) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL19827996 | 0.85 | ALDH1A1 (0.66) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL10718163 | 0.85 | ALDH1A1 (0.66) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL11198075 | 0.84 | ALDH1A1 (0.64) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL20239535 | 0.84 | MAOB (0.54) | SMN1; SMN2MAOBTDP1KMT2AMAOA | |
| SCHEMBL995678 | 0.83 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720439-B1 | EFFICIENT REDUCTION OF BASE SENSITIVE CARBONYL COMPOUNDS; SEPARATING RACEMIC CARBONYL COMPOUNDS; CHIRAL CATALYSTS | NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) | 2004-04-13 | — | — | US | disclosed |