Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 12/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 2/20 | 0.38 |
| ▸ | FNTB | P49356 | 2/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6833796 | 0.87 | ALDH1A1 (0.42) | MEN1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL505149 | 0.69 | GRM5 (0.49) | MEN1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL7064643 | 0.68 | MAOB (0.41) | ALDH1A1HPGD | |
| SCHEMBL504820 | 0.67 | GRM5 (0.54) | MEN1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL7413192 | 0.67 | MEN1 (0.50) | MEN1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL4261756 | 0.66 | GRM5 (0.48) | KMT2AHSP90AA1 | |
| SCHEMBL6918289 | 0.65 | SMN1; SMN2 (0.38) | MEN1ALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL2709528 | 0.64 | FNTA (0.49) | MEN1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL15055269 | 0.64 | PTGDR2 (0.61) | MEN1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL15056961 | 0.63 | PTGDR2 (0.60) | MEN1ALDH1A1GAAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |