SCHEMBL6918289

SCHEMBL6918289

N#Cc1ccc([AsH]C(=O)c2cc(CNCc3ccccc3)on2)c(C(=O)O)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.38
POLB P06746 1/20 0.38
LDHA P00338 1/20 0.37
LDHB P07195 1/20 0.37
VNN1 O95497 2/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
KDM4E B2RXH2 2/20 0.34
HTT P42858 2/20 0.34
ALDH1A1 P00352 1/20 0.34
GLA P06280 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CDK2 P24941 1/20 0.34
ABCB1 P08183 3/20 0.34
SCD O00767 2/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6834689 0.81 SMN1; SMN2 (0.43) SMN1; SMN2POLBLDHALDHBVNN1
SCHEMBL9548422 0.74 SMN1; SMN2 (0.53) SMN1; SMN2POLBLDHALDHBMEN1
SCHEMBL16143633 0.74 ALB (0.40) SMN1; SMN2MEN1KMT2AKDM4EALDH1A1
Trifluoroacetic Acid SCHEMBL6932186 0.70 ALB (0.37) SMN1; SMN2KDM4EALDH1A1HSD17B10CDK2
SCHEMBL6916075 0.69 ALDH1A1 (0.58) SMN1; SMN2MEN1KMT2AKDM4EHTT
SCHEMBL6914592 0.69 XDH (0.37) HTTALDH1A1HPGD
SCHEMBL7064643 0.69 MAOB (0.41) SMN1; SMN2ALDH1A1HPGD
SCHEMBL6833211 0.67 SMN1; SMN2 (0.46) SMN1; SMN2POLBMEN1KMT2AALDH1A1
SCHEMBL7121763 0.66 CCR2 (0.58)
SCHEMBL6919537 0.65 XDH (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004018428-A1 ANTIBACTERIAL BENZOIC ACID DERIVATIVES PHARMACIA & UPJOHN COMPANY LLC (US) 2004-03-04 WO disclosed