Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HPN | P05981 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27695001 | 0.80 | VCAM1 (0.52) | CA2CA1ALOX15HPNMAPT | |
| SCHEMBL9394376 | 0.77 | CA2 (0.59) | CA2CA1ALOX15HPNMAPT | |
| SCHEMBL9646002 | 0.75 | CA2 (0.57) | CA2CA1ALOX15HPNMAPT | |
| SCHEMBL28853602 | 0.74 | VCAM1 (0.54) | CA2CA1GAAVCAM1KMT2A | |
| SCHEMBL5027033 | 0.73 | VCAM1 (0.55) | CA2CA1ALOX15SMN1; SMN2GAA | |
| SCHEMBL100583 | 0.72 | CA2 (0.53) | CA2CA1ALOX15HPNMAPT | |
| SCHEMBL9648998 | 0.72 | CA2 (0.53) | CA2CA1ALOX15HPNMAPT | |
| SCHEMBL7155322 | 0.72 | VCAM1 (0.56) | CA2CA1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL11347714 | 0.72 | VCAM1 (0.56) | CA2CA1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL39477 | 0.72 | VCAM1 (0.56) | CA2CA1ALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026245-A2 | SUBSTITUTED PHOSPHONATE COMPOUNDS HAVING BONE ANABOLIC ACTIVITY | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | disclosed |
| EP-0638084-A1 | SUBSTITUTED PHOSPHONATES, THE PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1995-02-15 | — | — | EP | disclosed |