Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | STAT1 | P42224 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8159908 | 0.98 | MAPT (0.51) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2300900 | 0.86 | USP2 (0.54) | NPC1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL14157779 | 0.86 | GPR119 (0.54) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL23051649 | 0.84 | GPR119 (0.47) | MAPTALDH1A1SMN1; SMN2LMNAGPR119 | |
| SCHEMBL5536717 | 0.84 | ALDH1A1 (0.55) | MAPTALDH1A1LMNATSHRHSD17B10 | |
| SCHEMBL20443678 | 0.83 | USP2 (0.63) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7379091 | 0.83 | ALDH1A1 (0.51) | MAPTALDH1A1SMN1; SMN2TP53LMNA | |
| SCHEMBL12551039 | 0.83 | ALDH1A1 (0.71) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL23051648 | 0.83 | GPR119 (0.55) | MAPTALDH1A1SMN1; SMN2LMNAGPR119 | |
| SCHEMBL1930818 | 0.83 | GPR119 (0.46) | MAPTALDH1A1SMN1; SMN2LMNAGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | disclosed |