Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7640007 | 0.87 | — | — | |
| SCHEMBL5086735 | 0.79 | — | — | |
| SCHEMBL2905552 | 0.77 | — | — | |
| SCHEMBL6066261 | 0.74 | SIGMAR1 (0.33) | SIGMAR1KCNH2TP53MAOAMAOB | |
| SCHEMBL4465789 | 0.72 | SIGMAR1 (0.38) | SIGMAR1CETPKCNH2TLR8TP53 | |
| Butylbenzyl SCHEMBL9545214 | 0.71 | SIGMAR1 (0.57) | SIGMAR1KCNH2HSD11B1MAOAHPGD | |
| Butylbenzyl SCHEMBL10925942 | 0.71 | SIGMAR1 (0.57) | SIGMAR1KCNH2HSD11B1MAOAHPGD | |
| SCHEMBL6131261 | 0.69 | ALDH1A1 (0.57) | SIGMAR1KCNH2HSD11B1MAOAMAOB | |
| Butylbenzyl SCHEMBL22716183 | 0.69 | SIGMAR1 (0.59) | SIGMAR1KCNH2TP53HSD11B1MAOA | |
| Butylbenzyl SCHEMBL16051 | 0.69 | SIGMAR1 (0.59) | SIGMAR1KCNH2TP53HSD11B1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971962-B1 | CATALYST SYSTEM FOR HIGH YIELD SYNTHESIS OF POLYOLEFINS | BP CHEM INT LTD (GB) | 2004-02-11 | — | — | EP | disclosed |
| EP-0971962-A1 | CATALYST SYSTEM FOR HIGH YIELD SYNTHESIS OF POLYOLEFINS | THE DOW CHEMICAL COMPANY (US) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998045337-A1 | CATALYST SYSTEM FOR HIGH YIELD SYNTHESIS OF POLYOLEFINS | THE DOW CHEMICAL COMPANY (US) | 1998-10-15 | — | — | WO | disclosed |