Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2142520 | 0.70 | — | — | |
| SCHEMBL7514524 | 0.67 | TSHR (0.32) | TSHRALDH1A1 | |
| Glutaral SCHEMBL29229225 | 0.67 | HIF1A (0.62) | HIF1ATSHRFAAHTRPV1ALDH1A1 | |
| SCHEMBL4882722 | 0.67 | TSHR (0.50) | HIF1ATSHRFAAHTRPV1ALDH1A1 | |
| SCHEMBL1784079 | 0.65 | — | — | |
| SCHEMBL129074 | 0.65 | TSHR (0.62) | HIF1ATSHRFAAHTRPV1ALDH1A1 | |
| SCHEMBL7590459 | 0.65 | TSHR (0.55) | HIF1ATSHRFAAHTRPV1ALDH1A1 | |
| Glutaral SCHEMBL836 | 0.64 | — | — | |
| Glutaral SCHEMBL1285455 | 0.64 | HIF1A (1.00) | HIF1ATSHRFAAHTRPV1ALDH1A1 | |
| SCHEMBL16816939 | 0.64 | HIF1A (0.82) | HIF1ATSHRFAAHTRPV1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045569-B2 | Process of making modified metallocene catalyst, catalyst produced and use thereof | W. R. GRACE & CO.-CONN. (US) | 2015-06-02 | — | — | US | disclosed |
| US-20130289227-A1 | PROCESS OF MAKING MODIFIED METALLOCENE CATALYST, CATALYST PRODUCED AND USE THEREOF | W.R. GRACE & CO.-CONN (US) | 2013-10-31 | — | — | US | disclosed |
| US-6686306-B2 | Supported dual transition metal catalyst systems | W.R. GRACE & CO.- CONN. | 2004-02-03 | — | — | US | disclosed |
| US-6559090-B1 | Support-activator in agglomerate form and a metallocene and/or constrained geometry coordination catalyst component | W. R. GRACE & CO.-CONN. | 2003-05-06 | — | — | US | disclosed |