SCHEMBL6916478

SCHEMBL6916478

CN(C)Cc1ccccc1I.[MgH2]

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.49
SLC6A4 P31645 12/20 0.47
SLC6A2 P23975 11/20 0.47
ALDH1A1 P00352 2/20 0.46
TSHR P16473 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46
KMT2A Q03164 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TAAR1 Q96RJ0 1/20 0.45
SLC6A3 Q01959 7/20 0.44
IDO1 P14902 2/20 0.43
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9700565 0.98 SIGMAR1 (0.50) SIGMAR1SLC6A4SLC6A2ALDH1A1TSHR
SCHEMBL125255 0.80 ALDH1A1 (0.57) SLC6A4SLC6A2ALDH1A1TSHRKDM4E
SCHEMBL29729780 0.80 ALDH1A1 (0.57) SLC6A4SLC6A2ALDH1A1TSHRKDM4E
SCHEMBL3056915 0.76 TAAR1 (0.59) SIGMAR1TAAR1IDO1
SCHEMBL11270512 0.76 TSHR (0.48) SIGMAR1ALDH1A1TSHRKDM4EMEN1
SCHEMBL22711482 0.74 SLC6A4 (0.49) SLC6A4SLC6A2ALDH1A1TSHRKDM4E
SCHEMBL6045290 0.74 TAAR1 (0.46) SIGMAR1SLC6A4SLC6A2CYP2D6CYP2C19
SCHEMBL11259775 0.74 SIGMAR1 (0.46) SIGMAR1SLC6A4SLC6A2TSHRCYP3A4
SCHEMBL322185 0.74 NPC1 (0.46) SIGMAR1ALDH1A1KDM4EMEN1CYP2D6
Water SCHEMBL27915649 0.73 SLC6A4 (0.46) SLC6A4SLC6A2ALDH1A1TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004074333-A2 PROCESS FOR HOMO- OR COPOLYMERIZATIONOF CONJUGATED OLEFINES DOW GLOBAL TECHNOLOGIES INC. (US) 2004-09-02 WO disclosed