Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.34 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.34 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | PER2 | O15055 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4194088 | 0.80 | THRB (0.39) | PDK2THRBTSHRALDH1A1POLB | |
| SCHEMBL163326 | 0.78 | KMT2A (0.46) | THRBTSHRALDH1A1POLBGAA | |
| SCHEMBL16102000 | 0.78 | ALDH1A1 (0.39) | PDK2ALDH1A1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL4188784 | 0.77 | THRB (0.44) | THRBTSHRALDH1A1POLBATM | |
| SCHEMBL3507611 | 0.77 | PDK2 (0.41) | PDK2TSHRALDH1A1PRKAB2PRKAG1 | |
| SCHEMBL138215 | 0.77 | THRB (0.41) | PDK2THRBTSHRALDH1A1POLB | |
| SCHEMBL67735 | 0.76 | ATM (0.49) | THRBALDH1A1GAASMN1; SMN2ATM | |
| Fluoride SCHEMBL7527634 | 0.76 | ATM (0.49) | THRBALDH1A1GAASMN1; SMN2ATM | |
| SCHEMBL12515375 | 0.76 | KMT2A (0.40) | PDK2THRBTSHRALDH1A1POLB | |
| SCHEMBL16090933 | 0.76 | ALDH1A1 (0.41) | PDK2ALDH1A1PRKAB2PRKAG1PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686321-B2 | MIXTURE; LUBRICANT OIL ADDITIVE | CASTROL LIMITED (GB) | 2004-02-03 | — | — | US | claimed |
| US-4447582-A | QUATERNIZATION, CROSSLINKING | COPOLYMER RUBBER & CHEMICAL CORPORATION (US) | 1984-05-08 | — | — | US | claimed |
| US-6686321-B2 | MIXTURE; LUBRICANT OIL ADDITIVE | CASTROL LIMITED (GB) | 2004-02-03 | — | — | US | disclosed |
| US-4810754-A | CROSSLINKING INHIBITION | EXXON RESEARCH & ENGINEERING COMPANY (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0026613-B1 | METHOD OF GRAFTING EPM AND EPDM POLYMERS | COPOLYMER RUBBER & CHEMICAL CORPORATION (US) | 1984-11-21 | — | — | EP | disclosed |
| US-4464493-A | Process for dissolving EPM and EPDM polymers in oil | COPOLYMER RUBBER & CHEMICAL CORP. (US) | 1984-08-07 | — | — | US | disclosed |
| US-4447582-A | QUATERNIZATION, CROSSLINKING | COPOLYMER RUBBER & CHEMICAL CORPORATION (US) | 1984-05-08 | — | — | US | disclosed |
| US-4434064-A | GRINDING WITH OXYGEN | ATLANTIC RICHFIELD COMPANY (US) | 1984-02-28 | — | — | US | disclosed |
| US-4417991-A | NONTHICKENING, EXTREME PRESSURE LUBRICANTS | ATLANTIC RICHFIELD COMPANY (US) | 1983-11-29 | — | — | US | disclosed |
| US-4340689-A | Method of grafting EPM and EPDM polymers | COPOLYMER RUBBER & CHEMICAL CORPORATION (US) | 1982-07-20 | — | — | US | disclosed |
| EP-0026613-A1 | Method of grafting EPM and EPDM polymers | COPOLYMER RUBBER & CHEMICAL CORPORATION (US) | 1981-04-08 | — | — | EP | disclosed |
| US-4251644-A | Polar resins having improved characteristics by blending with EPM and EPDM polymers | COPOLYMER RUBBER & CHEMICAL CORPORATION (US) | 1981-02-17 | — | — | US | disclosed |
| US-4146489-A | LUBRICANTS, DISPERSANTS | ROHM AND HAAS COMPANY (US) | 1979-03-27 | — | — | US | disclosed |