Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 7/20 | 0.86 |
| ▸ | BLM | P54132 | 2/20 | 0.86 |
| ▸ | HBB | P68871 | 2/20 | 0.86 |
| ▸ | USP2 | O75604 | 1/20 | 0.86 |
| ▸ | TSHR | P16473 | 1/20 | 0.86 |
| ▸ | EDNRA | P25101 | 1/20 | 0.86 |
| ▸ | HTR2A | P28223 | 1/20 | 0.86 |
| ▸ | RECQL | P46063 | 1/20 | 0.86 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.86 |
| ▸ | HPRT1 | P00492 | 7/20 | 0.78 |
| ▸ | POLG | P54098 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | VCP | P55072 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acyclovir SCHEMBL145614 | 0.95 | PNP (0.91) | PNPBLMHBBUSP2TSHR | |
| Acyclovir SCHEMBL23440044 | 0.95 | PNP (0.91) | PNPBLMHBBUSP2TSHR | |
| Acyclovir SCHEMBL145606 | 0.95 | PNP (0.91) | PNPBLMHBBUSP2TSHR | |
| Acyclovir SCHEMBL543440 | 0.95 | PNP (0.91) | PNPBLMHBBUSP2TSHR | |
| Acyclovir SCHEMBL11310318 | 0.94 | PNP (0.88) | PNPBLMHBBUSP2TSHR | |
| Acyclovir SCHEMBL28326009 | 0.94 | PNP (0.88) | PNPBLMHBBUSP2TSHR | |
| Acyclovir SCHEMBL11310314 | 0.94 | PNP (0.88) | PNPBLMHBBUSP2TSHR | |
| Acyclovir SCHEMBL571377 | 0.93 | PNP (0.86) | PNPBLMHBBUSP2TSHR | |
| Acyclovir SCHEMBL3664893 | 0.93 | PNP (1.00) | PNPBLMHBBUSP2TSHR | |
| Acyclovir SCHEMBL3175 | 0.93 | PNP (1.00) | PNPBLMHBBUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1620515-A | Post-synthesis labeling of nucleic acids and uses thereof | AMERSHAM BIOSCIENCES AB (SE) | 2005-05-25 | — | — | CN | claimed |
| EP-1461455-A2 | POST-SYNTHESIS LABELING OF NUCLEIC ACIDS AND USES THEREOF | Amersham Biosciences AB (SE) | 2004-09-29 | — | — | EP | claimed |
| WO-2003052115-A2 | POST-SYNTHESIS LABELING OF NUCLEIC ACIDS AND USES THEREOF | AMERSHAM BIOSCIENCES AB (SE) | 2003-06-26 | — | — | WO | claimed |
| US-20030119005-A1 | Post-synthesis labeling of nucleic acids, assays using nucleic acids that are labeled post-synthetically, single nucleotide polymorphism detection, and associated compounds and microarrays | MOTOROLA, INC. | 2003-06-26 | — | — | US | claimed |