Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 17/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 17/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 17/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4983780 | 0.91 | ADRB2 (0.55) | MAPTADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL207184 | 0.86 | ADRB2 (0.68) | MAPTADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL27814469 | 0.85 | ADRB2 (0.49) | ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL22340408 | 0.85 | ADRB2 (0.58) | MAPTLMNAPOLBADRB2ADRB1 | |
| Acetic Acid SCHEMBL28698833 | 0.85 | ALDH1A1 (0.64) | LMNAADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL11470348 | 0.84 | ADRB2 (0.65) | LMNAADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL2788016 | 0.84 | MAPT (0.58) | MAPTADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL16769253 | 0.84 | ADRB2 (0.51) | MAPTADRB2ADRB1ADRB3 | |
| SCHEMBL2179812 | 0.83 | ADRB2 (0.69) | MAPTADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL2179816 | 0.83 | ADRB2 (0.69) | MAPTADRB2ADRB1ADRB3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720439-B1 | EFFICIENT REDUCTION OF BASE SENSITIVE CARBONYL COMPOUNDS; SEPARATING RACEMIC CARBONYL COMPOUNDS; CHIRAL CATALYSTS | NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) | 2004-04-13 | — | — | US | disclosed |