Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 7/20 | 0.38 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711411 | 0.95 | GPR35 (0.42) | GPR35MAP3K5TP53MAPTPOLB | |
| SCHEMBL6708559 | 0.95 | MAP3K5 (0.38) | GPR35MAP3K5TP53MAPTMAPK1 | |
| SCHEMBL6820655 | 0.89 | GAA (0.34) | MAP3K5TP53MAPTMAPK1TDP1 | |
| SCHEMBL6709867 | 0.88 | GPR35 (0.39) | GPR35MAP3K5TP53MAPTPOLB | |
| SCHEMBL6712466 | 0.87 | GPR35 (0.39) | GPR35MAP3K5TP53MAPTMAPK1 | |
| SCHEMBL6707737 | 0.87 | GPR35 (0.40) | GPR35MAP3K5TP53MAPTMAPK1 | |
| SCHEMBL6710241 | 0.86 | GPR35 (0.43) | GPR35MAP3K5TP53MAPTMAPK1 | |
| SCHEMBL6711904 | 0.86 | MAP3K5 (0.36) | GPR35MAP3K5TP53MAPTMAPK1 | |
| SCHEMBL6714268 | 0.85 | LMNA (0.39) | MAP3K5TP53MAPTPOLBLMNA | |
| SCHEMBL6712028 | 0.85 | MAP3K5 (0.38) | MAP3K5TP53MAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |