SCHEMBL6917643

SCHEMBL6917643

Cl[Zr](Cl)(C(c1ccccc1)c1ccccc1)(C1c2ccccc2-c2ccccc21)C1c2ccccc2-c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
POLB P06746 1/20 0.41
ATM Q13315 1/20 0.41
TSHR P16473 2/20 0.33
SLC22A2 O15244 1/20 0.33
SLC22A3 O75751 1/20 0.33
GPR3 P46089 1/20 0.32
HTR2A P28223 1/20 0.32
CYP1A2 P05177 1/20 0.32
CACNA1G O43497 2/20 0.31
ADORA3 P0DMS8 1/20 0.30
THRB P10828 1/20 0.30
CHRM1 P11229 1/20 0.30
TBXA2R P21731 1/20 0.30
PTGS1 P23219 1/20 0.30
ADRA1A P35348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7946949 0.69 SLC22A2 (0.38) MEN1KMT2APOLBATMSLC22A2
SCHEMBL4454243 0.68 SLC22A2 (0.39) MEN1KMT2APOLBATMTSHR
SCHEMBL6909725 0.65 SLC22A2 (0.33) MEN1KMT2APOLBATMTSHR
SCHEMBL3157929 0.64 MEN1 (0.52) MEN1KMT2APOLBATMTSHR
SCHEMBL3644683 0.64 SLC22A2 (0.39) MEN1KMT2APOLBATMSLC22A2
Hydrochloric Acid SCHEMBL7104041 0.64 GPR3 (0.43) MEN1KMT2APOLBATMSLC22A2
SCHEMBL163858 0.64 SLC22A2 (0.43) MEN1KMT2APOLBATMSLC22A2
SCHEMBL6906980 0.64 POLB (0.41) MEN1KMT2APOLBATMTSHR
SCHEMBL5998334 0.61 CHRNB4 (0.41) MEN1KMT2APOLBATMTSHR
SCHEMBL12259452 0.61 CYP1A2 (0.46) MEN1KMT2APOLBATMTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0927201-B1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM HYUNDAI PETROCHEMICAL CO LTD (KR) 2004-04-14 EP disclosed
EP-0927201-A1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM Hyundai Petrochemical Co., Ltd. (KR) 1999-07-07 EP disclosed
WO-1998009996-A1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM HYUNDAI PETROCHEMICAL CO., LTD. (KR) 1998-03-12 WO disclosed