SCHEMBL4454243

SCHEMBL4454243

CC=[Zr](Cl)(Cl)(C1c2ccccc2-c2ccccc21)C1c2ccccc2-c2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A2 O15244 1/20 0.39
SLC22A3 O75751 1/20 0.39
GPR3 P46089 2/20 0.39
POLB P06746 2/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
ATM Q13315 1/20 0.35
HTR2A P28223 1/20 0.34
ACHE P22303 2/20 0.32
SLC6A4 P31645 2/20 0.32
SLC6A3 Q01959 2/20 0.32
CHRM2 P08172 1/20 0.32
HTR1A P08908 1/20 0.32
ADRA2A P08913 1/20 0.32
CHRM1 P11229 1/20 0.32
DRD1 P21728 1/20 0.32
SLC6A2 P23975 1/20 0.32
ADRA1A P35348 1/20 0.32
OPRM1 P35372 1/20 0.32
DRD3 P35462 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6433417 0.84 SLC22A2 (0.30) SLC22A2SLC22A3
SCHEMBL651333 0.83 SLC22A2 (0.31) SLC22A2SLC22A3
SCHEMBL7192529 0.82 SLC22A2 (0.31) SLC22A2SLC22A3GPR3
SCHEMBL7943229 0.81 SLC22A2 (0.30) SLC22A2SLC22A3
SCHEMBL6447585 0.78 SLC22A2 (0.30) SLC22A2SLC22A3
SCHEMBL7192497 0.78
SCHEMBL6446479 0.77
SCHEMBL7199342 0.76 PTPN1 (0.33)
SCHEMBL6445006 0.75 HTR6 (0.30) SLC22A2SLC22A3
SCHEMBL7927053 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323524-B2 Tandem tetramerisation-polymerisation of olefins SASOL TECHNOLOGY (PTY) LIMITED (ZA) 2008-01-29 US claimed
US-20060128910-A1 Tandem tetramerisation-polymerisation of olefins SASOL TECHNOLOGY (PTY) LIMITED (ZA) 2006-06-15 US claimed
EP-1581343-A1 TANDEM TETRAMERISATION-POLYMERISATION OF OLEFINS Sasol Technology (PTY) Limited (ZA) 2005-10-05 EP claimed
WO-2004056480-A1 TANDEM TETRAMERISATION-POLYMERISATION OF OLEFINS SASOL TECHNOLOGY (PTY) LIMITED (ZA) 2004-07-08 WO claimed
US-10421921-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-09-24 US disclosed
EP-1920031-B1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS EXXONMOBIL CHEMICAL PATENTS INC (US) 2018-01-10 EP disclosed
US-20170137737-A1 Lubricants from Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2017-05-18 US disclosed
US-9593288-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-03-14 US disclosed
CN-102666561-B Transition metal complex, the cyclopentadiene compound of catalyst for trimerization and replacement SUMITOMO CHEMICAL CO.,LTD. (JP) 2015-11-25 CN disclosed
US-20150252279-A1 Lubricants From Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2015-09-10 US disclosed
US-8513478-B2 Process to produce polyalphaolefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-08-20 US disclosed
US-20090036725-A1 Process To Produce Polyalphaolefins EXXONMOBIL CHEMICAL PATENTS INC. 2009-02-05 US disclosed
WO-2007011832-A1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-01-25 WO disclosed
WO-2007011462-A1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-01-25 WO disclosed
US-20060128910-A1 Tandem tetramerisation-polymerisation of olefins SASOL TECHNOLOGY (PTY) LIMITED (ZA) 2006-06-15 US disclosed
EP-1581343-A1 TANDEM TETRAMERISATION-POLYMERISATION OF OLEFINS Sasol Technology (PTY) Limited (ZA) 2005-10-05 EP disclosed
WO-2004056480-A1 TANDEM TETRAMERISATION-POLYMERISATION OF OLEFINS SASOL TECHNOLOGY (PTY) LIMITED (ZA) 2004-07-08 WO disclosed
EP-0927201-B1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM HYUNDAI PETROCHEMICAL CO LTD (KR) 2004-04-14 EP disclosed
EP-0927201-A1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM Hyundai Petrochemical Co., Ltd. (KR) 1999-07-07 EP disclosed
WO-1998009996-A1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM HYUNDAI PETROCHEMICAL CO., LTD. (KR) 1998-03-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036725-A1 Process To Produce Polyalphaolefins KCNMA1, F10, AP2A1 SLC22A2 3708/4885SLC22A3 4311/4885GPR3 4414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.