Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 16/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6922482 | 0.80 | NISCH (0.54) | NISCH | |
| SCHEMBL11302206 | 0.77 | NISCH (0.62) | NISCHADRA1A | |
| SCHEMBL6920530 | 0.75 | NISCH (0.54) | NISCH | |
| SCHEMBL9579892 | 0.74 | NISCH (0.81) | NISCH | |
| SCHEMBL30617425 | 0.74 | CD274 (0.59) | NISCH | |
| SCHEMBL30980843 | 0.74 | CD274 (0.59) | NISCH | |
| SCHEMBL8887144 | 0.73 | NISCH (0.66) | NISCHKDM4ECYP1A2ADRA1A | |
| SCHEMBL3394014 | 0.71 | NISCH (0.65) | NISCH | |
| SCHEMBL1626317 | 0.70 | NISCH (1.00) | NISCH | |
| SCHEMBL9195272 | 0.70 | NISCH (0.53) | NISCHKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043947-A1 | NOVEL PYRIDINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043947-A1 | NOVEL PYRIDINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2004-05-27 | — | — | WO | disclosed |