Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 11/20 | 0.54 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6917821 | 0.80 | NISCH (0.54) | NISCH | |
| SCHEMBL4721393 | 0.77 | DHODH (0.58) | DHODHGRM4MEN1ALDH1A1GAA | |
| SCHEMBL9579892 | 0.75 | NISCH (0.81) | NISCH | |
| SCHEMBL11263510 | 0.73 | NISCH (0.71) | NISCHALDH1A1GAAADRA2AADRA2B | |
| SCHEMBL8887144 | 0.73 | NISCH (0.66) | NISCH | |
| SCHEMBL25381465 | 0.71 | DHODH (0.51) | DHODHGRM4MEN1ALDH1A1GAA | |
| SCHEMBL6920530 | 0.71 | NISCH (0.54) | NISCH | |
| SCHEMBL1821476 | 0.70 | DHODH (0.50) | DHODHGRM4MEN1ALDH1A1GAA | |
| SCHEMBL9195272 | 0.70 | NISCH (0.53) | NISCHALDH1A1MAPT | |
| SCHEMBL1036359 | 0.69 | ADRA2A (0.78) | ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043947-A1 | NOVEL PYRIDINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043947-A1 | NOVEL PYRIDINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2004-05-27 | — | — | WO | disclosed |