SCHEMBL6917865

SCHEMBL6917865

c1ccc([SiH](c2ccccc2)[Hf](C2c3ccccc3-c3ccccc32)C2c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.34
HTR2A P28223 1/20 0.34
CYP1A2 P05177 1/20 0.33
TSHR P16473 1/20 0.33
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
HDAC9 Q9UKV0 1/20 0.31
HDAC5 Q9UQL6 1/20 0.31
NCOR2 Q9Y618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6916996 0.74 GPR3 (0.41) GPR3HTR2ACYP1A2TSHRMEN1
Hydrochloric Acid SCHEMBL6434708 0.72 GPR3 (0.40) GPR3HTR2ACYP1A2TSHRMEN1
SCHEMBL23532439 0.67 GPR3 (0.38) GPR3HTR2ACYP1A2TSHRMEN1
SCHEMBL6903225 0.66 GPR3 (0.46) GPR3HTR2ACYP1A2TSHRMEN1
SCHEMBL4323084 0.66 GPR3 (0.41) GPR3HTR2ACYP1A2TSHRMEN1
Hydrochloric Acid SCHEMBL4443280 0.64 HTR6 (0.32) HTR2AMEN1KMT2A
SCHEMBL7066602 0.64 GPR3 (0.35) GPR3HTR2ACYP1A2TSHRMEN1
SCHEMBL9172533 0.64 GPR3 (0.35) GPR3HTR2ACYP1A2TSHRMEN1
SCHEMBL6919030 0.62 MEN1 (0.43) GPR3HTR2ACYP1A2TSHRMEN1
SCHEMBL21867278 0.61 HTR2A (0.38) GPR3HTR2ACYP1A2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0927201-B1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM HYUNDAI PETROCHEMICAL CO LTD (KR) 2004-04-14 EP disclosed
EP-0530908-B2 Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM NV (NL) 2003-06-04 EP disclosed
EP-0927201-A1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM Hyundai Petrochemical Co., Ltd. (KR) 1999-07-07 EP disclosed
EP-0530908-B1 Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM NV (NL) 1999-04-21 EP disclosed
WO-1998009996-A1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM HYUNDAI PETROCHEMICAL CO., LTD. (KR) 1998-03-12 WO disclosed
US-5646083-A Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM N.V. (NL) 1997-07-08 US disclosed
EP-0530908-A1 Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM N.V. (NL) 1993-03-10 EP disclosed