Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.43 |
| ▸ | SCD | O00767 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29943572 | 0.87 | RXFP1 (0.60) | RXFP1SIGMAR1CYP2C9CYP2C19HTR2B | |
| SCHEMBL25305 | 0.87 | RXFP1 (0.60) | RXFP1SIGMAR1CYP2C9CYP2C19HTR2B | |
| SCHEMBL3528330 | 0.86 | P2RX7 (0.55) | RXFP1SIGMAR1CYP2C9CYP2C19HTR2B | |
| Hydrochloric Acid SCHEMBL25425 | 0.85 | RXFP1 (0.59) | RXFP1SIGMAR1CYP2C9CYP2C19HTR2B | |
| Hydrochloric Acid SCHEMBL3529996 | 0.84 | P2RX7 (0.54) | RXFP1SIGMAR1CYP2C9CYP2C19HTR2B | |
| SCHEMBL7674982 | 0.83 | P2RX7 (0.46) | CYP2C9CYP2C19HTR2BMAPK14P2RX7 | |
| Trifluoroacetic Acid SCHEMBL27703342 | 0.82 | CYP2C9 (0.56) | RXFP1SIGMAR1CYP2C9CYP2C19HTR2B | |
| SCHEMBL938517 | 0.77 | LMNA (0.54) | RXFP1SIGMAR1CYP2C9CYP2C19HRH4 | |
| Tert-Butyl Formate SCHEMBL27728669 | 0.77 | RXFP1 (0.49) | RXFP1SIGMAR1CYP2C9CYP2C19HTR2B | |
| Tert-Butyl Formate SCHEMBL27697827 | 0.76 | P2RX7 (0.47) | RXFP1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | claimed |