SCHEMBL691832

SCHEMBL691832

[CH2]CCOCCC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL375634 0.86 LMNA (0.53)
SCHEMBL8694965 0.85 TSHR (0.42)
SCHEMBL8696479 0.85 TSHR (0.52)
SCHEMBL28778289 0.83 TSHR (0.50)
SCHEMBL1766170 0.83 LMNA (0.50)
SCHEMBL16134190 0.83 LMNA (0.50)
SCHEMBL1766172 0.83 LMNA (0.50)
SCHEMBL1766162 0.83 LMNA (0.50)
SCHEMBL22771166 0.83 LMNA (0.50)
SCHEMBL16134189 0.83 LMNA (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 416 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1347780-B1 COMPOSITIONS OF N-(METHYLETHYLAMINOCARBONYL)-4-(3-METHYLPHENYLAMINO)-3-PYRIDYLSULFONAMIDE AND CYCLIC OLIGOSACCHARIDES PLIVA PHARM & CHEM WORKS (HR) 2007-01-03 EP claimed
US-7037928-B2 Compositions of N-(methylethylaminocarbonyl)-4-(-3-methylphenylamino)-3-pyridylsulfonamide and cyclic oligosaccharides PLIVA, FARMACEUTSKA INDUSTRIJA, DIONICKO DRUSTVO (HR) 2006-05-02 US claimed
JP-2004513155-A 2004-04-30 JP claimed
US-20040039204-A1 Compositions of n-(methylethaylaminocarbonyl)-4-(-3-methylphenylamino)-3-pyridylsulfonamide and cyclic oligosacccharides PLIVA FARMACEUTSKA INDUSTRIJ, DIONICKO DRUSTVO (HR) 2004-02-26 US claimed
EP-1347780-A1 COMPOSITIONS OF N-(METHYLETHYLAMINOCARBONYL)-4-(3-METHYLPHENYLAMINO)-3-PYRIDYLSULFONAMIDE AND CYCLIC OLIGOSACCHARIDES Pliva, Farmaceutska, Industrija, Dionicko Drustvo (HR) 2003-10-01 EP claimed
WO-2002038186-A1 COMPOSITIONS OF N-(METHYLETHYLAMINOCARBONYL)-4-(3-METHYLPHENYLAMINO)-3-PYRIDYLSULFONAMIDE AND CYCLIC OLIGOSACCHARIDES PLIVA, FARMACEUTSKA INDUSTRIJA, DIONICKO DRUSTVO (HR) 2002-05-16 WO claimed
WO-1998035677-A1 NON-SEDATING HISTAMINE ANTAGONIST COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF BRIDGE PHARMA, INC. (US) 1998-08-20 WO claimed
US-11939324-B2 Compounds for the treatment of epilepsy, neurodegenerative disorders and other CNS disorders REMYND N.V. (BE) 2024-03-26 US disclosed
EP-3621963-B1 COMPOUNDS FOR THE TREATMENT OF EPILEPSY, NEURODEGENERATIVE DISORDERS AND OTHER CNS DISORDERS REMYND N V (BE) 2024-01-24 EP disclosed
WO-2023241799-A1 FLAVANOLS FOR USE IN THE TREATMENT OF RETROVIRAL INFECTIONS Université Libre de Bruxelles (BE) 2023-12-21 WO disclosed
US-20230130598-A1 PYRROLOPYRIDINE AND IMIDAZOPYRIDINE ANTIVIRAL COMPOUNDS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-04-27 US disclosed
US-20230099111-A1 COMPOUNDS FOR THE TREATMENT OF EPILEPSY, NEURODEGENERATIVE DISORDERS AND OTHER CNS DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-03-30 US disclosed
WO-2023046900-A1 RIBONUCLEOSIDE ANALOGUES AGAINST -SARS-COV-2 KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-03-30 WO disclosed
EP-0573473-A1 4- (2-BENZOTHIAZOLYL)METHYLAMINO]--g(a)- (3,4-DIFLUOROPHENOXY)METHYL]-1-PIPERIDINEETHANOL. JANSSEN PHARMACEUTICA NV (BE) 1993-12-15 EP disclosed
WO-1993019061-A1 ITRACONAZOLE AND SAPERCONAZOLE STEREOISOMERS JANSSEN PHARMACEUTICA N.V. (BE) 1993-09-30 WO disclosed
WO-1993009118-A1 1,3-DIHYDRO-2H-IMIDAZO(4,5-B)QUINOLIN-2-ONE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS JANSSEN PHARMACEUTICA N.V. (BE) 1993-05-13 WO disclosed
EP-0541153-A1 1,3-Dihydro-2H-imidazo[4,5-b]-quinolin-2-one derivatives as phosphodiesterase inhibitors JANSSEN PHARMACEUTICA N.V. (BE) 1993-05-12 EP disclosed
EP-0503710-A2 Flunarizine containing anti-neoplastic compositions JANSSEN PHARMACEUTICA N.V. (BE) 1992-09-16 EP disclosed
WO-1992014731-A1 4-[(2-BENZOTHIAZOLYL)METHYLAMINO]-α-[(3,4-DIFLUOROPHENOXY)METHYL]-1-PIPERIDINEETHANOL JANSSEN PHARMACEUTICA N.V. (BE) 1992-09-03 WO disclosed
EP-0501552-A1 4-[(2-Benzothiazolyl)methylamino]-alpha-[(3,4-difluorophenoxy)methyl]-1-piperidineethanol JANSSEN PHARMACEUTICA N.V. (BE) 1992-09-02 EP disclosed